T cell peripheral subsets in lichen sclerosus et atrophicus

T cell peripheral subsets in lichen sclerosus et atrophicus

Summary Peripheral blood T lymphocytes and T cell subsets were examined in 17 subjects with lichen sclerosus et atrophicus using monoclonal antibodies OKT3, OKT4, OKT8 The results were compared with those obtained from 17 healthy age‐and sex‐matched controls. The percentages of OKT3, and OKT8, cells...

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Veröffentlicht in:Clinical and experimental dermatology 1986-11, Vol.11 (6), p.569-573
Hauptverfasser: BETTI, R., LODI, A., MARMINI, A., MASNADA, M.C., ROSTI, A., TURRIN, D., CATTANEO, M.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Antibodies, Monoclonal
Biological and medical sciences
Child
Dermatitis, Atopic - immunology
Dermatology
Female
Humans
Male
Medical sciences
Middle Aged
Psoriasis. Parapsoriasis. Lichen
T-Lymphocytes - classification
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Beschreibung
Zusammenfassung:Summary Peripheral blood T lymphocytes and T cell subsets were examined in 17 subjects with lichen sclerosus et atrophicus using monoclonal antibodies OKT3, OKT4, OKT8 The results were compared with those obtained from 17 healthy age‐and sex‐matched controls. The percentages of OKT3, and OKT8, cells were significantly reduced in patients with LSA, A direct correlation between the degree of activity of the disease and percentages of OKT3+3, OKT4+, cells and the helper suppressor ratio was observed. These data are then discussed.
ISSN:0307-6938
1365-2230
DOI:10.1111/j.1365-2230.1986.tb00510.x