Bis(acetato)amminedichloro(cyclohexylamine)platinum(IV), an Orally Active Anticancer Drug

The structure of the anticancer drug bis(acetato)-amminedichloro(cyclohexylamine)platinum(IV), [PtCl2-(C2H3O2)2(C6H13N)(NH3)], is reported. The acetato groups are axial to the square plane composed of the chlorine and amine substituents. The cyclohexane ring may sterically hinder one of the acetato...

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Veröffentlicht in:	Acta crystallographica. Section C, Crystal structure communications Crystal structure communications, 1995-05, Vol.51 (5), p.822-824
Hauptverfasser:	Neidle, S., Snook, C. F., Murrer, B. A., Barnard, C. F. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Agents - chemistry Biological and medical sciences Chemical Phenomena Chemistry, Physical Chlorides - chemistry Condensed matter: structure, mechanical and thermal properties Crystallization Crystallography, X-Ray Exact sciences and technology General aspects Hydrogen Bonding Inorganic compounds Medical sciences Metal complexes Molecular Conformation Molecular Structure Organoplatinum Compounds - chemistry Pharmacology. Drug treatments Physics Structure of solids and liquids crystallography Structure of specific crystalline solids
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