Expression of somatostatin receptor 3 mRNA in the motorneurones of the rat spinal cord, and the sensory neurones of the spinal ganglia

At least five different types of somatostatin receptors (SSTRs): SSTR1-5 have been recently cloned. Here, we report the distribution of somatostatin receptor 3 (SSTR3) mRNA in spinal cord and spinal ganglia by in situ hybridization. We demonstrate the presence of this transcript in motorneurones of...

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Veröffentlicht in:	Brain research. Molecular brain research. 1995-03, Vol.29 (1), p.185-190
Hauptverfasser:	Señaris, R.M., Schindler, M., Humphrey, P.P.A., Emson, P.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain Stem - metabolism Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Dorsal root ganglia Fundamental and applied biological sciences. Psychology Ganglia, Spinal - cytology Ganglia, Spinal - metabolism In Situ Hybridization Motor Neurons - metabolism Neurons, Afferent - metabolism Polymerase Chain Reaction Rats Receptors, Somatostatin - genetics RNA, Messenger - metabolism RT-PCR Somatostatin receptor 3 Spinal cord Spinal Cord - cytology Spinal Cord - metabolism Transcription, Genetic Vertebrates: nervous system and sense organs
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Zusammenfassung:	At least five different types of somatostatin receptors (SSTRs): SSTR1-5 have been recently cloned. Here, we report the distribution of somatostatin receptor 3 (SSTR3) mRNA in spinal cord and spinal ganglia by in situ hybridization. We demonstrate the presence of this transcript in motorneurones of the spinal cord and other motor nuclei of the brain stem, and in the sensory neurones of the spinal ganglia. These data suggest a role for SSTR3 in motor and sensory functions.
ISSN:	0169-328X 1872-6941
DOI:	10.1016/0169-328X(94)00275-J