Schumanniofoside, the antisnake venom principle from the stem bark of Schumanniophyton magnificum harms

The methanol extract of the stem bark of Schumanniophyton magnificum and schumanniofoside, a chromone alkaloidal glycoside isolated from it, reduced the lethal effect of black cobra ( Naja melanoleuca) venom in mice. This effect is greatest when the venom is mixed and incubated with the extract or s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of ethnopharmacology 1986-11, Vol.18 (2), p.167-172
Hauptverfasser:	Akunyili, D.N., Akubue, P.I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal poisons toxicology. Antivenoms Animals Antivenins - administration & dosage Antivenins - pharmacology bark Biological and medical sciences Elapid Venoms - antagonists & inhibitors Female glycosides Glycosides - administration & dosage Glycosides - pharmacology Male Medical sciences medicinal plants Mice Miscellaneous pharmacology Plant Extracts - pharmacology Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) schumanniophyton magnificum snake bites Toxicology Tropical medicine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The methanol extract of the stem bark of Schumanniophyton magnificum and schumanniofoside, a chromone alkaloidal glycoside isolated from it, reduced the lethal effect of black cobra ( Naja melanoleuca) venom in mice. This effect is greatest when the venom is mixed and incubated with the extract or schumanniofoside. It is thought that the mode of action is by oxidative inactivation of the venom.
ISSN:	0378-8741 1872-7573
DOI:	10.1016/0378-8741(86)90028-0