Transmission of HIV in dialysis centre

In August, 1993, 13 dialysis patients at one dialysis centre in Colombia, South America, were found to be HIV positive, and this prompted an epidemiological investigation. We carried out a cohort study of all dialysis centre patients during January, 1992 to December, 1993 (epidemic period) to determ...

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Veröffentlicht in:The Lancet (British edition) 1995-06, Vol.345 (8962), p.1417-1422
Hauptverfasser: Velandia, M., Cárdenas, V., Fridkin, S.K., Bland, L., Jarvis, W., Boshell, J., Iglesias, A., Ramirez, G.
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Sprache:eng
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Zusammenfassung:In August, 1993, 13 dialysis patients at one dialysis centre in Colombia, South America, were found to be HIV positive, and this prompted an epidemiological investigation. We carried out a cohort study of all dialysis centre patients during January, 1992 to December, 1993 (epidemic period) to determine risk factors for HIV secronconversion. Haemodialysis and medical records were reviewed, dyalisis centre staff and surviving patients were interviewed, and dialysis practices were observed. Stored sera from all dialysis centre patients were tested for HIV antibody. 12 (52%) of 23 patients tested positive for HIV antibody by enzyme immunoassay and western blot during the epidemic period. Of the 23 tested, 9 (39%) converted from HIV antibody negative to positive (seroconverters) and 10 (44%) remained HIV negative (seronegatives). The HIV seroconversion rate was higher among patients dialysed at the centre while a new patient, who was HIV seropositive was dyalised there (90% vs 0%; p
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(95)92603-8