CM101, a polysaccharide antitumor agent, does not inhibit wound healing in murine models

CM101, a polysaccharide antitumor agent, does not inhibit wound healing in murine models

CM101 (previously called GBS toxin), a new anticancer polysaccharide that induces inflammatory reactions in neovasculature of tumors, does not cause similar reactions in neovasculature of healing wounds. It appears that treatment with CM101 will not interfere with normal wound healing in cancer pati...

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Veröffentlicht in:Journal of cancer research and clinical oncology 1995-04, Vol.121 (4), p.253-256
Hauptverfasser: QUINN, T. E, THURMAN, G. B, SUNDELL, A.-K, MINGHUA ZHANG, HELLERQVIST, C. G
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antineoplastic agents
Antineoplastic Agents - pharmacology
Biological and medical sciences
Carmine
Disease Models, Animal
Drug Implants
General aspects
Male
Medical sciences
Methylprednisolone - pharmacology
Mice
Mice, Inbred BALB C
Neovascularization, Pathologic - drug therapy
Pharmacology. Drug treatments
Polysaccharides, Bacterial - pharmacology
Polyvinyl Alcohol
Wound Healing - drug effects
Wound Healing - physiology
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Zusammenfassung:CM101 (previously called GBS toxin), a new anticancer polysaccharide that induces inflammatory reactions in neovasculature of tumors, does not cause similar reactions in neovasculature of healing wounds. It appears that treatment with CM101 will not interfere with normal wound healing in cancer patients.
ISSN:0171-5216
1432-1335
DOI:10.1007/BF01366971