A resolution of the ascertainment sampling problem I. Theory

We consider the “ascertainment problem” arising when families are sampled by a nonrandom sampling process and, for the purpose of estimating genetic parameters, some assumption must be made about the process by which families enter the sample. A resolution of this problem, involving conditioning the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Theoretical population biology 1986-12, Vol.30 (3), p.388-412
Hauptverfasser:	Ewens, W.J., Shute, Nereda C.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biometry Fundamental and applied biological sciences. Psychology Genetic Diseases, Inborn - genetics Genetics of eukaryotes. Biological and molecular evolution Genetics, Population Humans Models, Genetic Population genetics, reproduction patterns Sampling Studies Theories and miscellaneous
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We consider the “ascertainment problem” arising when families are sampled by a nonrandom sampling process and, for the purpose of estimating genetic parameters, some assumption must be made about the process by which families enter the sample. A resolution of this problem, involving conditioning the likelihood of the sample on that part of the data relevant to ascertainment, is put forward. Numerical examples illustrating the properties of the procedure are provided.
ISSN:	0040-5809 1096-0325
DOI:	10.1016/0040-5809(86)90042-0