Levels of soluble ICAM‐1 in atopic dermatitis A new marker for monitoring the clinical activity?

Levels of soluble intercellular adhesion molecule‐1 (sICAM‐1) were measured in sera from patients with an acute exacerbation of their atopic dermatitis (AD) (n= 16) on admission to and discharge from our department of dermatology. At admission, the sICAM‐1 levels in sera from patients with AD were slightly higher than those of the blood donors (n= 100) and dropped at discharge significantly (P= 0.014) after improvement of the skin conditions. Therefore, sICAM‐1 may be, together with soluble interleukin‐2 receptor (sIL‐2), eosinophilic cationic protein (ECP), and CD14, another marker for monitoring AD.