Primary germinoma of the brain: immunocytochemical demonstration of tumour cells in the cerebrospinal fluid

Primary germinoma of the brain: immunocytochemical demonstration of tumour cells in the cerebrospinal fluid

A patient is presented, who developed a suprasellar tumour. Stereotactical biopsy of the tumour revealed the diagnosis of a dysgerminoma. Immunocytochemical examination of the CSF showed neoplastic cells staining for human chorionic gonadotropin and for alpha-fetoprotein. The authors stress the poss...

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Veröffentlicht in:Clinical neurology and neurosurgery 1986, Vol.88 (4), p.263-265
Hauptverfasser: STARK, E, KNEHANS, A, WURSTER, U, PATZOLD, U
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
alpha-Fetoproteins - cerebrospinal fluid
Biological and medical sciences
Cerebral Ventricle Neoplasms - cerebrospinal fluid
Cerebral Ventricle Neoplasms - diagnosis
Cerebrospinal Fluid - cytology
Chorionic Gonadotropin - cerebrospinal fluid
Dysgerminoma - cerebrospinal fluid
Dysgerminoma - diagnosis
Histocytochemistry
Humans
Immunologic Techniques
Male
Medical sciences
Neurology
Tumors of the nervous system. Phacomatoses
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Zusammenfassung:A patient is presented, who developed a suprasellar tumour. Stereotactical biopsy of the tumour revealed the diagnosis of a dysgerminoma. Immunocytochemical examination of the CSF showed neoplastic cells staining for human chorionic gonadotropin and for alpha-fetoprotein. The authors stress the possibility to diagnose primary intracranial germ cell tumours without operation.
ISSN:0303-8467
1872-6968
DOI:10.1016/S0303-8467(86)80043-9