Autoantibodies to thyroid hormones: Association with falsely low hormone levels measured by ‘Amerlex’ assay

Autoantibodies to thyroxine (T4) and tri-iodothyronine (T3) were found in a 21-yr-old thyrotoxic woman who had paradoxically low T4 and T3 as measured in the ‘Amerlex’ solid phase radio-immunoassay. Though rare, thyroid hormone antibodies should be suspected if anomalous thyroid function results are...

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Veröffentlicht in:	Clinica chimica acta 1986-12, Vol.161 (2), p.239-242
Hauptverfasser:	Heyma, Paula, Harrison, Len C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Autoantibodies Autoantibodies - immunology Biological and medical sciences Endocrinology False Negative Reactions Female Graves Disease - immunology Humans Immunoprecipitation Immunosorbent Techniques Investigative techniques, diagnostic techniques (general aspects) Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Radioimmunoassay Reagent Kits, Diagnostic Thyroxine Thyroxine - blood Thyroxine - immunology Tri-iodothyranine Triiodothyronine - blood Triiodothyronine - immunology
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Beschreibung
Zusammenfassung:	Autoantibodies to thyroxine (T4) and tri-iodothyronine (T3) were found in a 21-yr-old thyrotoxic woman who had paradoxically low T4 and T3 as measured in the ‘Amerlex’ solid phase radio-immunoassay. Though rare, thyroid hormone antibodies should be suspected if anomalous thyroid function results are obtained and alternate assay procedures used.
ISSN:	0009-8981 1873-3492
DOI:	10.1016/0009-8981(86)90217-2