t(11;22) and Other Chromosomal Rearrangements in Ewing's Sarcoma
Abnormal karyotypes from 13 human cases of Ewing's sarcoma are reported in this paper. The t(11;22) was seen in 9 cases, with 2 additional cases containing only a del(22). Other abnormalities included trisomy of 1q, translocations to 19p13, deletions of 3p and 6q, and homogenously staining regi...
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Veröffentlicht in: | JNCI : Journal of the National Cancer Institute 1986-12, Vol.77 (6), p.1211-1215 |
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creator | Douglass, Edwin C. Valentine, Marc Green, Alexander A. Hayes, F. Ann Thompson, Elizabeth I. |
description | Abnormal karyotypes from 13 human cases of Ewing's sarcoma are reported in this paper. The t(11;22) was seen in 9 cases, with 2 additional cases containing only a del(22). Other abnormalities included trisomy of 1q, translocations to 19p13, deletions of 3p and 6q, and homogenously staining regions. |
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format | Article |
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Ann ; Thompson, Elizabeth I.</creator><creatorcontrib>Douglass, Edwin C. ; Valentine, Marc ; Green, Alexander A. ; Hayes, F. Ann ; Thompson, Elizabeth I.</creatorcontrib><description>Abnormal karyotypes from 13 human cases of Ewing's sarcoma are reported in this paper. The t(11;22) was seen in 9 cases, with 2 additional cases containing only a del(22). Other abnormalities included trisomy of 1q, translocations to 19p13, deletions of 3p and 6q, and homogenously staining regions.</description><identifier>ISSN: 0027-8874</identifier><identifier>EISSN: 1460-2105</identifier><identifier>DOI: 10.1093/jnci/77.6.1211</identifier><identifier>PMID: 3467113</identifier><language>eng</language><publisher>Cary, NC: Oxford University Press</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Child ; Chromosome Deletion ; Chromosomes, Human, Pair 11 ; Chromosomes, Human, Pair 22 ; Diseases of the osteoarticular system ; Female ; Humans ; Leukemia - genetics ; Male ; Medical sciences ; Sarcoma, Ewing - genetics ; Translocation, Genetic ; Tumors of striated muscle and skeleton</subject><ispartof>JNCI : Journal of the National Cancer Institute, 1986-12, Vol.77 (6), p.1211-1215</ispartof><rights>1988 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7424139$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3467113$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Douglass, Edwin C.</creatorcontrib><creatorcontrib>Valentine, Marc</creatorcontrib><creatorcontrib>Green, Alexander A.</creatorcontrib><creatorcontrib>Hayes, F. 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Other abnormalities included trisomy of 1q, translocations to 19p13, deletions of 3p and 6q, and homogenously staining regions.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Chromosome Deletion</subject><subject>Chromosomes, Human, Pair 11</subject><subject>Chromosomes, Human, Pair 22</subject><subject>Diseases of the osteoarticular system</subject><subject>Female</subject><subject>Humans</subject><subject>Leukemia - genetics</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Sarcoma, Ewing - genetics</subject><subject>Translocation, Genetic</subject><subject>Tumors of striated muscle and skeleton</subject><issn>0027-8874</issn><issn>1460-2105</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9z0tLAzEUBeAgSq3VrTthFuJjMW1ek8zgRhn6EAoVq1DchDSTtKnzqMkU9d870qF3c7mcjwsHgEsE-wgmZLAplR1w3md9hBE6Al1EGQwxgtEx6EKIeRjHnJ6CM-83sJkE0w7oEMo4QqQLHus7hB4wvg9kmQWzeq1dkK5dVVS-KmQevGrpnCxXutBl7QNbBsNvW65ufTCXTjXkHJwYmXt90e4eeB8N39JJOJ2Nn9OnaWgxJ3XIYsgMU5IkRsVcQhUtzZJHhmiNkUoyShPzfxi-hDyjREOpMeOZVlGCCY1JD9zs_25d9bXTvhaF9UrnuSx1tfOCc4wTgnADr1q4WxY6E1tnC-l-RVu5ya_bXHolc9O0U9YfGKeYIpI0LNwz62v9c4il-xSMEx6JyeJDTEaLl3Q6nosx-QNfLXMF</recordid><startdate>19861201</startdate><enddate>19861201</enddate><creator>Douglass, Edwin C.</creator><creator>Valentine, Marc</creator><creator>Green, Alexander A.</creator><creator>Hayes, F. 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Ann</au><au>Thompson, Elizabeth I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>t(11;22) and Other Chromosomal Rearrangements in Ewing's Sarcoma</atitle><jtitle>JNCI : Journal of the National Cancer Institute</jtitle><addtitle>Journal of the National Cancer Institute</addtitle><date>1986-12-01</date><risdate>1986</risdate><volume>77</volume><issue>6</issue><spage>1211</spage><epage>1215</epage><pages>1211-1215</pages><issn>0027-8874</issn><eissn>1460-2105</eissn><abstract>Abnormal karyotypes from 13 human cases of Ewing's sarcoma are reported in this paper. The t(11;22) was seen in 9 cases, with 2 additional cases containing only a del(22). Other abnormalities included trisomy of 1q, translocations to 19p13, deletions of 3p and 6q, and homogenously staining regions.</abstract><cop>Cary, NC</cop><pub>Oxford University Press</pub><pmid>3467113</pmid><doi>10.1093/jnci/77.6.1211</doi><tpages>5</tpages></addata></record> |
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subjects | Adolescent Adult Biological and medical sciences Child Chromosome Deletion Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 22 Diseases of the osteoarticular system Female Humans Leukemia - genetics Male Medical sciences Sarcoma, Ewing - genetics Translocation, Genetic Tumors of striated muscle and skeleton |
title | t(11;22) and Other Chromosomal Rearrangements in Ewing's Sarcoma |
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