t(11;22) and Other Chromosomal Rearrangements in Ewing's Sarcoma

Abnormal karyotypes from 13 human cases of Ewing's sarcoma are reported in this paper. The t(11;22) was seen in 9 cases, with 2 additional cases containing only a del(22). Other abnormalities included trisomy of 1q, translocations to 19p13, deletions of 3p and 6q, and homogenously staining regi...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1986-12, Vol.77 (6), p.1211-1215
Hauptverfasser:	Douglass, Edwin C., Valentine, Marc, Green, Alexander A., Hayes, F. Ann, Thompson, Elizabeth I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Child Chromosome Deletion Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 22 Diseases of the osteoarticular system Female Humans Leukemia - genetics Male Medical sciences Sarcoma, Ewing - genetics Translocation, Genetic Tumors of striated muscle and skeleton
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Zusammenfassung:	Abnormal karyotypes from 13 human cases of Ewing's sarcoma are reported in this paper. The t(11;22) was seen in 9 cases, with 2 additional cases containing only a del(22). Other abnormalities included trisomy of 1q, translocations to 19p13, deletions of 3p and 6q, and homogenously staining regions.
ISSN:	0027-8874 1460-2105
DOI:	10.1093/jnci/77.6.1211