Biosynthesis of immunoreactive luteinizing hormone in the rat central nervous system
It was reported earlier that luteinizing hormone (LH) is detected in the bovine pineal gland, identical with pituitary LH with respect to immunochemical, physicochemical, and biological properties, LH has also been detected in various structures of the central nervous system and in the visceral orga...
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| Veröffentlicht in: | Neuroscience and behavioral physiology 1986-07, Vol.16 (4), p.298-301 |
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| container_title | Neuroscience and behavioral physiology |
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| creator | Nabatchikova, N A Krivosheev, O G |
| description | It was reported earlier that luteinizing hormone (LH) is detected in the bovine pineal gland, identical with pituitary LH with respect to immunochemical, physicochemical, and biological properties, LH has also been detected in various structures of the central nervous system and in the visceral organs in hypophysectomized rats. In response to the administration of luliberin to hypophysectomized rats, LH is detected in the blood in amounts exceeding the basal level of LH in hypophysectomized animals. In connection with this, extrapituitary sources of LH in the rat organism can be hypothesized. The purpose of the present communication was to present the results of investigations in search of the sites of extrapituitary synthesis of LH in the central nervous system. |
| doi_str_mv | 10.1007/BF01148172 |
| format | Article |
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In response to the administration of luliberin to hypophysectomized rats, LH is detected in the blood in amounts exceeding the basal level of LH in hypophysectomized animals. In connection with this, extrapituitary sources of LH in the rat organism can be hypothesized. The purpose of the present communication was to present the results of investigations in search of the sites of extrapituitary synthesis of LH in the central nervous system.</description><identifier>ISSN: 0097-0549</identifier><identifier>EISSN: 1573-899X</identifier><identifier>DOI: 10.1007/BF01148172</identifier><identifier>PMID: 3540702</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Brain - metabolism ; Cerebral Cortex - metabolism ; Corpus Striatum - metabolism ; Gonadotropin-Releasing Hormone - pharmacology ; Hypothalamus - metabolism ; In Vitro Techniques ; Luteinizing Hormone - biosynthesis ; Pineal Gland - metabolism ; Puromycin - pharmacology ; Rats ; Thalamus - metabolism</subject><ispartof>Neuroscience and behavioral physiology, 1986-07, Vol.16 (4), p.298-301</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c187t-934c0ecd6d0f710f0cb30a9e8cf1264358510baca97147bae5ba94ce2ea07fb53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3540702$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nabatchikova, N A</creatorcontrib><creatorcontrib>Krivosheev, O G</creatorcontrib><title>Biosynthesis of immunoreactive luteinizing hormone in the rat central nervous system</title><title>Neuroscience and behavioral physiology</title><addtitle>Neurosci Behav Physiol</addtitle><description>It was reported earlier that luteinizing hormone (LH) is detected in the bovine pineal gland, identical with pituitary LH with respect to immunochemical, physicochemical, and biological properties, LH has also been detected in various structures of the central nervous system and in the visceral organs in hypophysectomized rats. In response to the administration of luliberin to hypophysectomized rats, LH is detected in the blood in amounts exceeding the basal level of LH in hypophysectomized animals. In connection with this, extrapituitary sources of LH in the rat organism can be hypothesized. The purpose of the present communication was to present the results of investigations in search of the sites of extrapituitary synthesis of LH in the central nervous system.</description><subject>Animals</subject><subject>Brain - metabolism</subject><subject>Cerebral Cortex - metabolism</subject><subject>Corpus Striatum - metabolism</subject><subject>Gonadotropin-Releasing Hormone - pharmacology</subject><subject>Hypothalamus - metabolism</subject><subject>In Vitro Techniques</subject><subject>Luteinizing Hormone - biosynthesis</subject><subject>Pineal Gland - metabolism</subject><subject>Puromycin - pharmacology</subject><subject>Rats</subject><subject>Thalamus - metabolism</subject><issn>0097-0549</issn><issn>1573-899X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0M9LwzAYxvEgypzTi3chJw9C9U2TLs1Rh79g4GWCt5Jmb12kTWaSDuZfb2VDj57ey4eHly8h5wyuGYC8uXsAxkTJZH5AxqyQPCuVejskYwAlMyiEOiYnMX7AgGUJIzLihQAJ-Zgs7qyPW5dWGG2kvqG263rnA2qT7AZp2ye0zn5Z905XPnTeIbWODp4GnahBl4JuqcOw8X2kcRsTdqfkqNFtxLP9nZDXh_vF7Cmbvzw-z27nmWGlTJniwgCa5XQJjWTQgKk5aIWlaVg-FbwoCwa1NlpJJmStsai1EgZz1CCbuuATcrnbXQf_2WNMVWejwbbVDodvKinzvATg_0ImpoJxCQO82kETfIwBm2odbKfDtmJQ_bSu_loP-GK_2tcdLn_pPi7_BkyPepg</recordid><startdate>198607</startdate><enddate>198607</enddate><creator>Nabatchikova, N A</creator><creator>Krivosheev, O G</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>198607</creationdate><title>Biosynthesis of immunoreactive luteinizing hormone in the rat central nervous system</title><author>Nabatchikova, N A ; Krivosheev, O G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c187t-934c0ecd6d0f710f0cb30a9e8cf1264358510baca97147bae5ba94ce2ea07fb53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Animals</topic><topic>Brain - metabolism</topic><topic>Cerebral Cortex - metabolism</topic><topic>Corpus Striatum - metabolism</topic><topic>Gonadotropin-Releasing Hormone - pharmacology</topic><topic>Hypothalamus - metabolism</topic><topic>In Vitro Techniques</topic><topic>Luteinizing Hormone - biosynthesis</topic><topic>Pineal Gland - metabolism</topic><topic>Puromycin - pharmacology</topic><topic>Rats</topic><topic>Thalamus - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nabatchikova, N A</creatorcontrib><creatorcontrib>Krivosheev, O G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience and behavioral physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nabatchikova, N A</au><au>Krivosheev, O G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biosynthesis of immunoreactive luteinizing hormone in the rat central nervous system</atitle><jtitle>Neuroscience and behavioral physiology</jtitle><addtitle>Neurosci Behav Physiol</addtitle><date>1986-07</date><risdate>1986</risdate><volume>16</volume><issue>4</issue><spage>298</spage><epage>301</epage><pages>298-301</pages><issn>0097-0549</issn><eissn>1573-899X</eissn><abstract>It was reported earlier that luteinizing hormone (LH) is detected in the bovine pineal gland, identical with pituitary LH with respect to immunochemical, physicochemical, and biological properties, LH has also been detected in various structures of the central nervous system and in the visceral organs in hypophysectomized rats. In response to the administration of luliberin to hypophysectomized rats, LH is detected in the blood in amounts exceeding the basal level of LH in hypophysectomized animals. In connection with this, extrapituitary sources of LH in the rat organism can be hypothesized. The purpose of the present communication was to present the results of investigations in search of the sites of extrapituitary synthesis of LH in the central nervous system.</abstract><cop>United States</cop><pmid>3540702</pmid><doi>10.1007/BF01148172</doi><tpages>4</tpages></addata></record> |
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| ispartof | Neuroscience and behavioral physiology, 1986-07, Vol.16 (4), p.298-301 |
| issn | 0097-0549 1573-899X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77228003 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Animals Brain - metabolism Cerebral Cortex - metabolism Corpus Striatum - metabolism Gonadotropin-Releasing Hormone - pharmacology Hypothalamus - metabolism In Vitro Techniques Luteinizing Hormone - biosynthesis Pineal Gland - metabolism Puromycin - pharmacology Rats Thalamus - metabolism |
| title | Biosynthesis of immunoreactive luteinizing hormone in the rat central nervous system |
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