Diphtheria immunity in UK blood donors

Diphtheria immunity in UK blood donors

Immunity to diphtheria was determined in serum samples from 1000 UK-born blood donors at the North London Blood Transfusion Centre during a three-month period in 1993; 125 women and 125 men were stratified in 10-year age groups, from 20 to 59. A tissue (vero cell)-culture toxin- neutralisation assay...

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Veröffentlicht in:The Lancet (British edition) 1995-04, Vol.345 (8955), p.963-965
Hauptverfasser: Maple, P.A., Efstratiou, A., George, R.C., Andrews, N.J., Sesardic, D.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Antitoxins
Bacterial diseases
Biological and medical sciences
Blood & organ donations
Blood Donors
Diphtheria
Diphtheria - immunology
Disease
Female
Herd immunity
Human bacterial diseases
Humans
Immunity
Immunity (Disease)
Immunity, Active
Immunization
Infectious diseases
Male
Medical research
Medical sciences
Middle Aged
Miscellaneous
Public health
Studies
Toxins
United Kingdom
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Zusammenfassung:Immunity to diphtheria was determined in serum samples from 1000 UK-born blood donors at the North London Blood Transfusion Centre during a three-month period in 1993; 125 women and 125 men were stratified in 10-year age groups, from 20 to 59. A tissue (vero cell)-culture toxin- neutralisation assay was used to measure serum diphtheria antitoxin concentrations. According to internationally accepted definitions (antitoxin
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(95)90705-X