The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+-channel proteins

Heart rate is slowed in part by acetylcholine-dependent activation of a cardiac potassium (K + ) channel, I KACh . Activated muscarinic receptors stimulate l KAch via the G-protein βγ-subunits. It has been assumed that the inwardly rectifying K + -channel gene, GIRK1 , alone encodes I KAch -It is no...

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