New Onoceranoid Triterpene Constituents from Lansium domesticum

Three new natural onoceranoid triterpenes, lansionic acid (1), 3beta-hydroxyonocera-8(26),14-dien-21-one (2), and 21alpha-hydroxyonocera-8(26),14-dien-3-one (3), were isolated from the fruit peel of Lansium domesticum together with two known triterpenoids (4 and 5), and their structures were elucida...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2002-11, Vol.65 (11), p.1709-1711
Hauptverfasser:	TANAKA, Tadamitsu, ISHIBASHI, Masami, FUJIMOTO, Haruhiro, OKUYAMA, Emi, KOYANO, Takashi, KOWITHAYAKORN, Thaworn, HAYASHI, Masahiko, KOMIYAMA, Kanki
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Artemia - drug effects Biological and medical sciences Chemical constitution Fruit - chemistry Fundamental and applied biological sciences. Psychology Medical sciences Meliaceae - chemistry Molecular Structure Nuclear Magnetic Resonance, Biomolecular Other biological molecules Plant physiology and development Plant poisons toxicology Spectrophotometry, Infrared Terpenes, steroids. Hormones Thailand Toxicology Triterpenes - chemistry Triterpenes - isolation & purification Triterpenes - pharmacology
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Zusammenfassung:	Three new natural onoceranoid triterpenes, lansionic acid (1), 3beta-hydroxyonocera-8(26),14-dien-21-one (2), and 21alpha-hydroxyonocera-8(26),14-dien-3-one (3), were isolated from the fruit peel of Lansium domesticum together with two known triterpenoids (4 and 5), and their structures were elucidated from spectral data. These triterpenoids exhibited mild toxicity against brine shrimp (Artemia salina).
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np020239o