Relationship between changes in GIP concentrations and changes in insulin and C-peptide concentrations after guar gum therapy

Relationship between changes in GIP concentrations and changes in insulin and C-peptide concentrations after guar gum therapy

In order to elucidate the mechanisms of the action of gel-forming fibre in diabetes, we measured insulin, C-peptide and GIP responses to meals during treatment with guar gum and placebo in normal and non-insulin-dependent diabetic (NIDD) subjects. Dietary supplementation with guar gum caused a susta...

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Veröffentlicht in:Scandinavian journal of clinical and laboratory investigation 1986, Vol.46 (6), p.505-510
Hauptverfasser: Groop<, P. H., Groop<, L., Tötterman, K. J., Fyhrquist, F.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
C-peptide
C-Peptide - blood
Clinical Trials as Topic
Diabetes Mellitus, Type 1 - blood
Diabetes Mellitus, Type 1 - diet therapy
dietary fibre
Female
Galactans - therapeutic use
Gastric Inhibitory Polypeptide - blood
General and cellular metabolism. Vitamins
GIP
Glucagon - blood
guar gum
Humans
Insulin - blood
Lipids - blood
Male
Mannans - therapeutic use
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Plant Gums
Random Allocation
serum cholesterol
Type 2 (non-insulin-dependent) diabetes
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Zusammenfassung:In order to elucidate the mechanisms of the action of gel-forming fibre in diabetes, we measured insulin, C-peptide and GIP responses to meals during treatment with guar gum and placebo in normal and non-insulin-dependent diabetic (NIDD) subjects. Dietary supplementation with guar gum caused a sustained reduction of the GIP response in normal and diabetic subjects (p
ISSN:0036-5513
1502-7686
DOI:10.3109/00365518609083705