Octreotide in the management of orthostatic hypotension in multiple system atrophy : pilot trial of chronic administration

The aim of the study was to determine the potential effect of octreotide chronic administration on the functional prognosis of patients suffering from multiple system atrophy (MSA) with orthostatic hypotension (OH). Five patients received octreotide (100 micrograms s.c. injections t.i.d.) during 6 m...

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Veröffentlicht in:	Clinical neuropharmacology 1994-08, Vol.17 (4), p.380-383
Hauptverfasser:	BORDET, R, BENHADJALI, J, LIBERSA, C, DESTEE, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atrophy - complications Atrophy - drug therapy Biological and medical sciences Cardiovascular system Central Nervous System Diseases - complications Central Nervous System Diseases - drug therapy Drug Administration Schedule Female Hormones - therapeutic use Humans Hypotension, Orthostatic - drug therapy Hypotension, Orthostatic - etiology Male Medical sciences Miscellaneous Octreotide - therapeutic use Pharmacology. Drug treatments Pilot Projects Space life sciences
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Zusammenfassung:	The aim of the study was to determine the potential effect of octreotide chronic administration on the functional prognosis of patients suffering from multiple system atrophy (MSA) with orthostatic hypotension (OH). Five patients received octreotide (100 micrograms s.c. injections t.i.d.) during 6 months in an open trial. Patients experienced functional improvement after 6 months of treatment. All of them continued to receive octreotide after the 6-month evaluation period (mean duration: 12 months).
ISSN:	0362-5664 1537-162X