Electron transfer reaction of cytochrome c peroxidase at tin oxide electrodes

The unmediated one-electron reduction and reoxidation of ferric cytochrome c peroxidase at fluoride-doped tin oxide electrodes is reported. A long range interfacial electron transfer distance of 17Å is postulated by analogy to the Poulos/Kraut model for the cytochrome c peroxidase/cytochrome c electron transfer complex. The utility of the interfacial electrochemical approach for investigating cytochrome c peroxidase electron transfer behavior is discussed.