Insulin requirements in 242 patients with type II diabetes mellitus

The purpose of this study was to determine the subcutaneous insulin requirements for rapid, effective regulation of blood glucose in patients with poorly controlled type II diabetes mellitus by using an intravenous insulin infusion protocol. The insulin infusion achieved a mean (+/-SD) overnight blood glucose concentration of 101 +/- 15 mg/dL and 24-hour glucose concentration of 118 +/- 18 mg/dL. The intravenous insulin requirement of 81 +/- 32 U/day correlated well (P