Cutaneous lesions and blood count changes in a 9-month old girl with glutaric aciduria type I

Non-specific cutaneous lesions are common in patients suffering from acute myeloid leukemia (AML). Leukemic skin infiltrates are present in about 30% of cases of monoblastic or myelomonocytic leukemia. The appearance of specific skin lesions can precede bone marrow involvement. We report the case of...

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Veröffentlicht in:	Klinische Pädiatrie 2001-03, Vol.213 (2), p.74-75
Hauptverfasser:	Landmann, E, Kreuder, J, Gortner, L, Neugebauer, M, Reiter, A, Blütters-Sawatzki, R
Format:	Artikel
Sprache:	ger
Schlagworte:	Amino Acid Metabolism, Inborn Errors - complications Amino Acid Metabolism, Inborn Errors - diagnosis Amino Acid Metabolism, Inborn Errors - urine Anemia - etiology Diagnosis, Differential Female Glutarates - urine Humans Infant Leukemia - diagnosis Leukemia - etiology Leukemia - pathology Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - pathology Leukemic Infiltration Leukopenia - etiology Oxidoreductases - deficiency Skin - enzymology Skin - pathology
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Zusammenfassung:	Non-specific cutaneous lesions are common in patients suffering from acute myeloid leukemia (AML). Leukemic skin infiltrates are present in about 30% of cases of monoblastic or myelomonocytic leukemia. The appearance of specific skin lesions can precede bone marrow involvement. We report the case of a 9-month-old girl with acute myelogenous leukemia (FAB M5) and glutaric aciduria type I which initially presented with cutaneous lesions, anemia and leukopenia.
ISSN:	0300-8630
DOI:	10.1055/s-2001-12880