Effect of protease inhibitors combined with standard antiretroviral therapy on linear growth and weight gain in human immunodeficiency virus type 1-infected children
Children with HIV-1 infection and poor growth have a significant increase in the risk of death. We studied the effects of protease inhibitors on the height and weight of 27 HIV-1-infected children and found that in our small pilot study, protease inhibitor therapy had a positive effect on the height...
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| Veröffentlicht in: | The Pediatric infectious disease journal 2001-03, Vol.20 (3), p.315-316 |
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| container_end_page | 316 |
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| container_issue | 3 |
| container_start_page | 315 |
| container_title | The Pediatric infectious disease journal |
| container_volume | 20 |
| creator | DREIMANE, Daina NIELSEN, Karin DEVEIKIS, Audra BRYSON, Yvonne J GEFFNER, Mitchell E |
| description | Children with HIV-1 infection and poor growth have a significant increase in the risk of death. We studied the effects of protease inhibitors on the height and weight of 27 HIV-1-infected children and found that in our small pilot study, protease inhibitor therapy had a positive effect on the heights of HIV-1-infected children. Accelerated height velocity was sustained for at least 18 to 20 months. |
| doi_str_mv | 10.1097/00006454-200103000-00020 |
| format | Article |
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Antiparasitic agents ; Antiviral agents ; Biological and medical sciences ; Body Height - drug effects ; Body Weight - drug effects ; Child ; Child, Preschool ; Drug Therapy, Combination ; Female ; Growth Disorders - etiology ; Growth Disorders - prevention & control ; HIV Infections - complications ; HIV Infections - drug therapy ; HIV Infections - immunology ; Humans ; Infant ; Male ; Medical sciences ; Pharmacology. 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Antiparasitic agents</subject><subject>Antiviral agents</subject><subject>Biological and medical sciences</subject><subject>Body Height - drug effects</subject><subject>Body Weight - drug effects</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Growth Disorders - etiology</subject><subject>Growth Disorders - prevention & control</subject><subject>HIV Infections - complications</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - immunology</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pharmacology. 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| fulltext | fulltext |
| identifier | ISSN: 0891-3668 |
| ispartof | The Pediatric infectious disease journal, 2001-03, Vol.20 (3), p.315-316 |
| issn | 0891-3668 1532-0987 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77054032 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Body Height - drug effects Body Weight - drug effects Child Child, Preschool Drug Therapy, Combination Female Growth Disorders - etiology Growth Disorders - prevention & control HIV Infections - complications HIV Infections - drug therapy HIV Infections - immunology Humans Infant Male Medical sciences Pharmacology. Drug treatments Pilot Projects Protease Inhibitors - pharmacology Protease Inhibitors - therapeutic use Retrospective Studies Viral Load |
| title | Effect of protease inhibitors combined with standard antiretroviral therapy on linear growth and weight gain in human immunodeficiency virus type 1-infected children |
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