Effects of the Magenstrasse and Mill operation for obesity on plasma leptin and insulin resistance

Summary Background We evaluated the effect of the Magenstrasse and Mill (M & M) operation–a new form of non‐banded vertical gastroplasty–on weight loss, plasma leptin levels and insulin resistance. Methods Fasting plasma glucose, leptin and insulin levels were measured in 12 normal controls, 39 morbidly obese patients and 39 patients a median 3 years after the M & M procedure. Insulin resistance was calculated by the homeostasis model insulin resistance index. Results Body mass index mean (s.d.) decreased significantly (p