Maternal Smoking Leads to Increased Cord Serum IgG3

Maternal Smoking Leads to Increased Cord Serum IgG3

IgG subclass levels in cord serum of unselected European newborns were studied in relation to parental smoking. Cord IgG3 was significantly (P < 0.01) higher in newborns of smoking mothers (n= 18; geom.mean = 87.0%) compared to those of non‐smoking mothers (n= 66; geom.mean = 61.0%). Maternal smo...

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Veröffentlicht in:Allergy (Copenhagen) 1986-05, Vol.41 (4), p.302-307
Hauptverfasser: Magnusson, C. G. M., Johansson, S. G. O.
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
cord serum
Female
Fetal Blood - immunology
Humans
IgG subclasses
immunoassay
Immunoglobulin G - metabolism
Infant, Newborn
latex agglutination
Maternal-Fetal Exchange
Medical sciences
Pregnancy
Smoking
Tobacco, tobacco smoking
Toxicology
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Zusammenfassung:IgG subclass levels in cord serum of unselected European newborns were studied in relation to parental smoking. Cord IgG3 was significantly (P < 0.01) higher in newborns of smoking mothers (n= 18; geom.mean = 87.0%) compared to those of non‐smoking mothers (n= 66; geom.mean = 61.0%). Maternal smoking did not influence (P > 0.10) cord IgG2 or cord IgG4. Paternal smoking did not affect any of the three immunoglobulins in cord serum (P > 0.10). These data suggest that tobacco smoking affects IgG3 synthesis in some direct or indirect way.
ISSN:0105-4538
1398-9995
DOI:10.1111/j.1398-9995.1986.tb02033.x