A genetic analysis of the Epworth Sleepiness Scale in 1560 World War II male veteran twins in the NAS–NRC Twin Registry

Responses to the eight‐item Epworth Sleepiness Scale (ESS) obtained from 1560 World War II male veteran twin pairs [818 monozygotic (MZ), 742 dizygotic (DZ)] were analysed to determine the extent to which genetic influences are involved in self‐reported daytime sleepiness in the elderly. Average ESS...

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Veröffentlicht in:Journal of sleep research 2001-03, Vol.10 (1), p.53-58
Hauptverfasser: Carmelli, Dorit, Bliwise, Donald L., Swan, Gary E., Reed, Terry
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Sprache:eng
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Zusammenfassung:Responses to the eight‐item Epworth Sleepiness Scale (ESS) obtained from 1560 World War II male veteran twin pairs [818 monozygotic (MZ), 742 dizygotic (DZ)] were analysed to determine the extent to which genetic influences are involved in self‐reported daytime sleepiness in the elderly. Average ESS score (± SD) in this sample was 7.1 ± 3.9, range 0–24. More than half of the twins (65%–67%) reported a moderate to high chance of falling asleep while lying down to rest; fewer than 3% admitted that this would occur while sitting and talking to someone or while stopped in traffic. Daytime sleepiness was not associated with age but was significantly and positively associated with obesity. The intraclass twin correlation on ESS scores was 0.39 in MZ pairs and 0.21 in DZ pairs (both P 
ISSN:0962-1105
1365-2869
DOI:10.1046/j.1365-2869.2001.00241.x