Isolation of a gene encoding a putative polyamine transporter from Candida albicans, GPT1

A gene encoding a transport protein from the pathogenic yeast, Candida albicans, has been isolated during a complementation experiment utilizing an ornithine decarboxylase‐negative (spe1Δ) strain of Saccharomyces cerevisiae. This gene restores γ‐aminobutyric acid (GABA) transport to a GABA transport...

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Veröffentlicht in:Yeast (Chichester, England) England), 2001-04, Vol.18 (6), p.555-561
Hauptverfasser: McNemar, Mark D., Gorman, Jessica A., Buckley, Helen R.
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Sprache:eng
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Zusammenfassung:A gene encoding a transport protein from the pathogenic yeast, Candida albicans, has been isolated during a complementation experiment utilizing an ornithine decarboxylase‐negative (spe1Δ) strain of Saccharomyces cerevisiae. This gene restores γ‐aminobutyric acid (GABA) transport to a GABA transport‐negative mutant of S. cerevisiae and encodes a protein which putatively allows transport of one or more of the polyamines. We have assigned the name GPT1 (GABA/polyamine transporter) to this gene. The GenBank Accession No. for this gene is AF080132. Copyright © 2001 John Wiley & Sons, Ltd.
ISSN:0749-503X
1097-0061
DOI:10.1002/yea.697