An investigation on the biological activity of Combretum species
Leaf extracts of 20 Combretum species, many of which are used in southern African traditional medicine, were screened for anti-inflammatory, anthelmintic, anti-bilharzia (antischistosomal) and DNA-damaging activity. Significant activity in more than one bioassay was exhibited by Combretum apiculatum...
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| Veröffentlicht in: | Journal of ethnopharmacology 2001-04, Vol.75 (1), p.45-50 |
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| container_issue | 1 |
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| container_title | Journal of ethnopharmacology |
| container_volume | 75 |
| creator | McGaw, L.J Rabe, T Sparg, S.G Jäger, A.K Eloff, J.N van Staden, J |
| description | Leaf extracts of 20
Combretum species, many of which are used in southern African traditional medicine, were screened for anti-inflammatory, anthelmintic, anti-bilharzia (antischistosomal) and DNA-damaging activity. Significant activity in more than one bioassay was exhibited by
Combretum apiculatum,
Combretum hereroense,
Combretum molle and
Combretum mossambicense. Ethyl acetate extracts were generally most active, followed by acetone and then water extracts. |
| doi_str_mv | 10.1016/S0378-8741(00)00405-0 |
| format | Article |
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Combretum species, many of which are used in southern African traditional medicine, were screened for anti-inflammatory, anthelmintic, anti-bilharzia (antischistosomal) and DNA-damaging activity. Significant activity in more than one bioassay was exhibited by
Combretum apiculatum,
Combretum hereroense,
Combretum molle and
Combretum mossambicense. Ethyl acetate extracts were generally most active, followed by acetone and then water extracts.</description><identifier>ISSN: 0378-8741</identifier><identifier>EISSN: 1872-7573</identifier><identifier>DOI: 10.1016/S0378-8741(00)00405-0</identifier><identifier>PMID: 11282442</identifier><identifier>CODEN: JOETD7</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Animals ; Anthelmintic ; Anthelmintics - pharmacology ; Anti-bilharzia ; Anti-cancer ; Anti-inflammatory ; Anti-Inflammatory Agents, Non-Steroidal - pharmacology ; Biological and medical sciences ; Combretum ; DNA Damage ; General pharmacology ; Medical sciences ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Plant Extracts - pharmacology ; Rosales - chemistry ; Schistosoma haematobium - drug effects ; Species Specificity ; Traditional medicine</subject><ispartof>Journal of ethnopharmacology, 2001-04, Vol.75 (1), p.45-50</ispartof><rights>2001 Elsevier Science Ireland Ltd</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-3ffac36bfa34a3e5086111511865449098bdee063dc6021fd53b70173b03c6f83</citedby><cites>FETCH-LOGICAL-c389t-3ffac36bfa34a3e5086111511865449098bdee063dc6021fd53b70173b03c6f83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0378874100004050$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=969124$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11282442$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McGaw, L.J</creatorcontrib><creatorcontrib>Rabe, T</creatorcontrib><creatorcontrib>Sparg, S.G</creatorcontrib><creatorcontrib>Jäger, A.K</creatorcontrib><creatorcontrib>Eloff, J.N</creatorcontrib><creatorcontrib>van Staden, J</creatorcontrib><title>An investigation on the biological activity of Combretum species</title><title>Journal of ethnopharmacology</title><addtitle>J Ethnopharmacol</addtitle><description>Leaf extracts of 20
Combretum species, many of which are used in southern African traditional medicine, were screened for anti-inflammatory, anthelmintic, anti-bilharzia (antischistosomal) and DNA-damaging activity. Significant activity in more than one bioassay was exhibited by
Combretum apiculatum,
Combretum hereroense,
Combretum molle and
Combretum mossambicense. Ethyl acetate extracts were generally most active, followed by acetone and then water extracts.</description><subject>Animals</subject><subject>Anthelmintic</subject><subject>Anthelmintics - pharmacology</subject><subject>Anti-bilharzia</subject><subject>Anti-cancer</subject><subject>Anti-inflammatory</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Combretum</subject><subject>DNA Damage</subject><subject>General pharmacology</subject><subject>Medical sciences</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Plant Extracts - pharmacology</subject><subject>Rosales - chemistry</subject><subject>Schistosoma haematobium - drug effects</subject><subject>Species Specificity</subject><subject>Traditional medicine</subject><issn>0378-8741</issn><issn>1872-7573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0E1r3DAQgGFREppt2p_QYgiE9uB0xpIt-ZSEJV8QyKHtWcjyKFWxrY3kXci_jza7JMeCQJdnpOFl7CvCGQI2P38Bl6pUUuB3gB8AAuoSPrAFKlmVspb8gC3eyBH7lNI_AJAo4CM7QqxUJUS1YBeXU-GnDaXZP5rZh6nIZ_5LRefDEB69NUNh7Ow3fn4ugiuWYewizeuxSCuyntJndujMkOjL_j5mf66vfi9vy_uHm7vl5X1puWrnkjtnLG86Z7gwnGpQDSLWiKqphWihVV1PBA3vbQMVur7mnQSUvANuG6f4MTvdvbuK4Wmd99WjT5aGwUwU1knLrNuq5hnWO2hjSCmS06voRxOfNYLeptOv6fS2iwbQr-k05Llv-w_W3Uj9-9S-VQYne2BSzuKimaxPb65tWqxEVuc7RTnGxlPUKWeaLPU-kp11H_x_FnkBPNaJIw</recordid><startdate>20010401</startdate><enddate>20010401</enddate><creator>McGaw, L.J</creator><creator>Rabe, T</creator><creator>Sparg, S.G</creator><creator>Jäger, A.K</creator><creator>Eloff, J.N</creator><creator>van Staden, J</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010401</creationdate><title>An investigation on the biological activity of Combretum species</title><author>McGaw, L.J ; Rabe, T ; Sparg, S.G ; Jäger, A.K ; Eloff, J.N ; van Staden, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-3ffac36bfa34a3e5086111511865449098bdee063dc6021fd53b70173b03c6f83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Animals</topic><topic>Anthelmintic</topic><topic>Anthelmintics - pharmacology</topic><topic>Anti-bilharzia</topic><topic>Anti-cancer</topic><topic>Anti-inflammatory</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Combretum</topic><topic>DNA Damage</topic><topic>General pharmacology</topic><topic>Medical sciences</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Plant Extracts - pharmacology</topic><topic>Rosales - chemistry</topic><topic>Schistosoma haematobium - drug effects</topic><topic>Species Specificity</topic><topic>Traditional medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McGaw, L.J</creatorcontrib><creatorcontrib>Rabe, T</creatorcontrib><creatorcontrib>Sparg, S.G</creatorcontrib><creatorcontrib>Jäger, A.K</creatorcontrib><creatorcontrib>Eloff, J.N</creatorcontrib><creatorcontrib>van Staden, J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of ethnopharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McGaw, L.J</au><au>Rabe, T</au><au>Sparg, S.G</au><au>Jäger, A.K</au><au>Eloff, J.N</au><au>van Staden, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An investigation on the biological activity of Combretum species</atitle><jtitle>Journal of ethnopharmacology</jtitle><addtitle>J Ethnopharmacol</addtitle><date>2001-04-01</date><risdate>2001</risdate><volume>75</volume><issue>1</issue><spage>45</spage><epage>50</epage><pages>45-50</pages><issn>0378-8741</issn><eissn>1872-7573</eissn><coden>JOETD7</coden><abstract>Leaf extracts of 20
Combretum species, many of which are used in southern African traditional medicine, were screened for anti-inflammatory, anthelmintic, anti-bilharzia (antischistosomal) and DNA-damaging activity. Significant activity in more than one bioassay was exhibited by
Combretum apiculatum,
Combretum hereroense,
Combretum molle and
Combretum mossambicense. Ethyl acetate extracts were generally most active, followed by acetone and then water extracts.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>11282442</pmid><doi>10.1016/S0378-8741(00)00405-0</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0378-8741 |
| ispartof | Journal of ethnopharmacology, 2001-04, Vol.75 (1), p.45-50 |
| issn | 0378-8741 1872-7573 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Anthelmintic Anthelmintics - pharmacology Anti-bilharzia Anti-cancer Anti-inflammatory Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biological and medical sciences Combretum DNA Damage General pharmacology Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Rosales - chemistry Schistosoma haematobium - drug effects Species Specificity Traditional medicine |
| title | An investigation on the biological activity of Combretum species |
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