An investigation on the biological activity of Combretum species

An investigation on the biological activity of Combretum species

Leaf extracts of 20 Combretum species, many of which are used in southern African traditional medicine, were screened for anti-inflammatory, anthelmintic, anti-bilharzia (antischistosomal) and DNA-damaging activity. Significant activity in more than one bioassay was exhibited by Combretum apiculatum...

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Veröffentlicht in:Journal of ethnopharmacology 2001-04, Vol.75 (1), p.45-50
Hauptverfasser: McGaw, L.J, Rabe, T, Sparg, S.G, Jäger, A.K, Eloff, J.N, van Staden, J
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Anthelmintic
Anthelmintics - pharmacology
Anti-bilharzia
Anti-cancer
Anti-inflammatory
Anti-Inflammatory Agents, Non-Steroidal - pharmacology
Biological and medical sciences
Combretum
DNA Damage
General pharmacology
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Extracts - pharmacology
Rosales - chemistry
Schistosoma haematobium - drug effects
Species Specificity
Traditional medicine
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Zusammenfassung:Leaf extracts of 20 Combretum species, many of which are used in southern African traditional medicine, were screened for anti-inflammatory, anthelmintic, anti-bilharzia (antischistosomal) and DNA-damaging activity. Significant activity in more than one bioassay was exhibited by Combretum apiculatum, Combretum hereroense, Combretum molle and Combretum mossambicense. Ethyl acetate extracts were generally most active, followed by acetone and then water extracts.
ISSN:0378-8741
1872-7573
DOI:10.1016/S0378-8741(00)00405-0