Outcomes following staged bilateral pallidotomy in advanced Parkinson's disease
The authors assessed clinical outcome for up to one year after staged bilateral pallidotomy in 14 patients with advanced PD. One year after surgery, dyskinesias were virtually abolished and there were significant reductions in "off" time (67%) and activities of daily living "off"...
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| Veröffentlicht in: | Neurology 2001-03, Vol.56 (6), p.799-802 |
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| container_title | Neurology |
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| creator | COUNIHAN, T. J SHINOBU, L. A ESKANDAR, E. N COSGROVE, G. R PENNEY, J. B |
| description | The authors assessed clinical outcome for up to one year after staged bilateral pallidotomy in 14 patients with advanced PD. One year after surgery, dyskinesias were virtually abolished and there were significant reductions in "off" time (67%) and activities of daily living "off" scores (24%), as well as nonsignificant reduction in "off" motor score (39%); "on" scores were unchanged. One patient developed a visual field deficit; two had transient confusion. Staged bilateral pallidotomy improves motor function in selected patients with advanced PD. |
| doi_str_mv | 10.1212/WNL.56.6.799 |
| format | Article |
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Staged bilateral pallidotomy improves motor function in selected patients with advanced PD.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Functional Laterality - physiology</subject><subject>Globus Pallidus - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Movement - physiology</subject><subject>Neurosurgery</subject><subject>Parkinson Disease - physiopathology</subject><subject>Parkinson Disease - surgery</subject><subject>Prognosis</subject><subject>Skull, brain, vascular surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Graft diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>COUNIHAN, T. J</creatorcontrib><creatorcontrib>SHINOBU, L. A</creatorcontrib><creatorcontrib>ESKANDAR, E. N</creatorcontrib><creatorcontrib>COSGROVE, G. R</creatorcontrib><creatorcontrib>PENNEY, J. B</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>COUNIHAN, T. J</au><au>SHINOBU, L. A</au><au>ESKANDAR, E. N</au><au>COSGROVE, G. R</au><au>PENNEY, J. B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcomes following staged bilateral pallidotomy in advanced Parkinson's disease</atitle><jtitle>Neurology</jtitle><addtitle>Neurology</addtitle><date>2001-03-27</date><risdate>2001</risdate><volume>56</volume><issue>6</issue><spage>799</spage><epage>802</epage><pages>799-802</pages><issn>0028-3878</issn><eissn>1526-632X</eissn><coden>NEURAI</coden><abstract>The authors assessed clinical outcome for up to one year after staged bilateral pallidotomy in 14 patients with advanced PD. One year after surgery, dyskinesias were virtually abolished and there were significant reductions in "off" time (67%) and activities of daily living "off" scores (24%), as well as nonsignificant reduction in "off" motor score (39%); "on" scores were unchanged. One patient developed a visual field deficit; two had transient confusion. Staged bilateral pallidotomy improves motor function in selected patients with advanced PD.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>11274323</pmid><doi>10.1212/WNL.56.6.799</doi><tpages>4</tpages></addata></record> |
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| ispartof | Neurology, 2001-03, Vol.56 (6), p.799-802 |
| issn | 0028-3878 1526-632X |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection; Journals@Ovid Complete |
| subjects | Adult Aged Biological and medical sciences Female Follow-Up Studies Functional Laterality - physiology Globus Pallidus - surgery Humans Male Medical sciences Middle Aged Movement - physiology Neurosurgery Parkinson Disease - physiopathology Parkinson Disease - surgery Prognosis Skull, brain, vascular surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases |
| title | Outcomes following staged bilateral pallidotomy in advanced Parkinson's disease |
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