Thyroxine-induced changes in rat liver mitochondrial ubiquinone

Thyroxine-induced changes in rat liver mitochondrial ubiquinone

Ubiquinone was extracted from liver mitochondria isolated from euthyroid and hyperthyroid rats. The redox state of ubiquinone was determined during States III and IV respiration with succinate or glutamate-malate substrates. Ubiquinone was more reduced during State III or IV in the hyperthyroid mito...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biochemical and biophysical research communications 1986-07, Vol.138 (1), p.381-386
Hauptverfasser: Horrum, Mark A., Tobin, Richard B., Ecklund, Robert E.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Applied sciences
Exact sciences and technology
Glutamates - metabolism
Glutamic Acid
Hyperthyroidism - metabolism
Malates - metabolism
Male
Mitochondria, Liver - drug effects
Mitochondria, Liver - metabolism
Other techniques and industries
Oxidation-Reduction
Oxygen Consumption - drug effects
Rats
Rats, Inbred Strains
Succinates - metabolism
Succinic Acid
Thyroxine - pharmacology
Ubiquinone - metabolism
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Ubiquinone was extracted from liver mitochondria isolated from euthyroid and hyperthyroid rats. The redox state of ubiquinone was determined during States III and IV respiration with succinate or glutamate-malate substrates. Ubiquinone was more reduced during State III or IV in the hyperthyroid mitochondria with either substrate. Furthermore, the concentration of ubiquinone increased in the hyperthyroid rats.
ISSN:0006-291X
1090-2104
DOI:10.1016/0006-291X(86)90292-5