The management of cutaneous leishmaniasis from Belize
We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR...
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| Veröffentlicht in: | Clinical and experimental dermatology 2001-01, Vol.26 (1), p.16-20 |
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| container_title | Clinical and experimental dermatology |
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| creator | Palmer, R. A. Tran, D. Hepburn, N. C. Ashton, R. E. |
| description | We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely positive, so treatment should not be based on PCR alone. Of the 20 cases 18 were healed 6 weeks after intravenous sodium stibogluconate 20 mg/kg per day for 20 days. We present a management protocol. |
| doi_str_mv | 10.1046/j.1365-2230.2001.00751.x |
| format | Article |
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E.</creatorcontrib><title>The management of cutaneous leishmaniasis from Belize</title><title>Clinical and experimental dermatology</title><addtitle>Clin Exp Dermatol</addtitle><description>We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely positive, so treatment should not be based on PCR alone. Of the 20 cases 18 were healed 6 weeks after intravenous sodium stibogluconate 20 mg/kg per day for 20 days. 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E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The management of cutaneous leishmaniasis from Belize</atitle><jtitle>Clinical and experimental dermatology</jtitle><addtitle>Clin Exp Dermatol</addtitle><date>2001-01</date><risdate>2001</risdate><volume>26</volume><issue>1</issue><spage>16</spage><epage>20</epage><pages>16-20</pages><issn>0307-6938</issn><eissn>1365-2230</eissn><coden>CEDEDE</coden><abstract>We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely positive, so treatment should not be based on PCR alone. Of the 20 cases 18 were healed 6 weeks after intravenous sodium stibogluconate 20 mg/kg per day for 20 days. 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| fulltext | fulltext |
| identifier | ISSN: 0307-6938 |
| ispartof | Clinical and experimental dermatology, 2001-01, Vol.26 (1), p.16-20 |
| issn | 0307-6938 1365-2230 |
| language | eng |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Adolescent Adult Antimony Sodium Gluconate - administration & dosage Antiprotozoal Agents - therapeutic use Biological and medical sciences Human protozoal diseases Humans Infectious diseases Leishmaniasis, Cutaneous - diagnosis Leishmaniasis, Cutaneous - drug therapy Leshmaniasis Medical Records Medical sciences Middle Aged Parasitic diseases Polymerase Chain Reaction Protozoal diseases Retrospective Studies Treatment Outcome Tropical medicine |
| title | The management of cutaneous leishmaniasis from Belize |
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