The management of cutaneous leishmaniasis from Belize

We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR...

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Veröffentlicht in:Clinical and experimental dermatology 2001-01, Vol.26 (1), p.16-20
Hauptverfasser: Palmer, R. A., Tran, D., Hepburn, N. C., Ashton, R. E.
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Sprache:eng
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Zusammenfassung:We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely positive, so treatment should not be based on PCR alone. Of the 20 cases 18 were healed 6 weeks after intravenous sodium stibogluconate 20 mg/kg per day for 20 days. We present a management protocol.
ISSN:0307-6938
1365-2230
DOI:10.1046/j.1365-2230.2001.00751.x