An HPLC/UV method for the determination of RGH-1756 in dog and rat plasma

RGH-1756 (1-(2-methoxy-phenyl)-4-{4-[4-(6-imidazo[2,1-b]-thiazolyl)-phenoxy]-butyl}-piperazine dimethansulphonate) is a novel atypical antipsychotic candidate of Gedeon Richter Ltd. A new HPLC method has been developed and validated for the quantitative determination of RGH-1756 in dog and rat plasm...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2001-03, Vol.24 (5), p.913-920
Hauptverfasser:	TERJEKI, Etelka, KAPAS, Margit
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antipsychotic Agents - blood Antipsychotic Agents - pharmacokinetics Biological and medical sciences Biological Availability Calibration Chromatography, High Pressure Liquid - methods Dog Dogs Female General pharmacology HPLC Male Medical sciences Method validation Pharmacology. Drug treatments Piperazines - blood Piperazines - pharmacokinetics Rat Rats Rats, Wistar Reproducibility of Results RGH-1756 Sensitivity and Specificity Spectrophotometry, Ultraviolet - methods Thiazoles - blood Thiazoles - pharmacokinetics
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