Early Diagnosis of Acute Postoperative Renal Transplant Rejection by Indium-111-Labeled Platelet Scintigraphy
A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA an...
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| Veröffentlicht in: | The Journal of nuclear medicine (1978) 1986-08, Vol.27 (8), p.1266-1272 |
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| container_end_page | 1272 |
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| container_issue | 8 |
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| container_title | The Journal of nuclear medicine (1978) |
| container_volume | 27 |
| creator | Tisdale, Patricia L Collier, B. David Kauffman, H. Myron Adams, Mark B Isitman, Ali T Hellman, Robert S Hoffmann, Raymond G Rao, Shyam A Joestgen, Thomas Krohn, Linda |
| description | A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA and [131I]orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival. |
| format | Article |
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David ; Kauffman, H. Myron ; Adams, Mark B ; Isitman, Ali T ; Hellman, Robert S ; Hoffmann, Raymond G ; Rao, Shyam A ; Joestgen, Thomas ; Krohn, Linda</creator><creatorcontrib>Tisdale, Patricia L ; Collier, B. David ; Kauffman, H. Myron ; Adams, Mark B ; Isitman, Ali T ; Hellman, Robert S ; Hoffmann, Raymond G ; Rao, Shyam A ; Joestgen, Thomas ; Krohn, Linda</creatorcontrib><description>A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA and [131I]orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.</description><identifier>ISSN: 0161-5505</identifier><identifier>EISSN: 1535-5667</identifier><identifier>PMID: 3525780</identifier><language>eng</language><publisher>United States: Soc Nuclear Med</publisher><subject>Acute Disease ; Adolescent ; Adult ; Blood Platelets ; Female ; Graft Rejection ; Humans ; Indium ; Kidney - diagnostic imaging ; Kidney Transplantation ; Male ; Middle Aged ; Postoperative Period ; Prospective Studies ; Radioisotopes ; Radionuclide Imaging</subject><ispartof>The Journal of nuclear medicine (1978), 1986-08, Vol.27 (8), p.1266-1272</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3525780$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tisdale, Patricia L</creatorcontrib><creatorcontrib>Collier, B. David</creatorcontrib><creatorcontrib>Kauffman, H. Myron</creatorcontrib><creatorcontrib>Adams, Mark B</creatorcontrib><creatorcontrib>Isitman, Ali T</creatorcontrib><creatorcontrib>Hellman, Robert S</creatorcontrib><creatorcontrib>Hoffmann, Raymond G</creatorcontrib><creatorcontrib>Rao, Shyam A</creatorcontrib><creatorcontrib>Joestgen, Thomas</creatorcontrib><creatorcontrib>Krohn, Linda</creatorcontrib><title>Early Diagnosis of Acute Postoperative Renal Transplant Rejection by Indium-111-Labeled Platelet Scintigraphy</title><title>The Journal of nuclear medicine (1978)</title><addtitle>J Nucl Med</addtitle><description>A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA and [131I]orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.</description><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Blood Platelets</subject><subject>Female</subject><subject>Graft Rejection</subject><subject>Humans</subject><subject>Indium</subject><subject>Kidney - diagnostic imaging</subject><subject>Kidney Transplantation</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Period</subject><subject>Prospective Studies</subject><subject>Radioisotopes</subject><subject>Radionuclide Imaging</subject><issn>0161-5505</issn><issn>1535-5667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotkF1LwzAUhoMoc05_gpArvSokaZOml2PODxg4dF6XND3dMtK0JqnSf29luzov53k4HN4LNKc85QkXIr9Ec0IFTTgn_BrdhHAkhAgp5QzNUs54LskctWvl7YifjNq7LpiAuwYv9RABb7sQux68iuYH8Ac4ZfHOKxd6q1ycFkfQ0XQOVyN-c7UZ2oRSmmxUBRZqvLUqTiHiT21cNHuv-sN4i64aZQPcnecCfT2vd6vXZPP-8rZabpIDS2VMMgDGa6krLmSuUlGnBVCgjawoB9GIuqGZEAURWklWkKaAIssKmYFWNVUyTxfo4XS39933ACGWrQka7PQ5dEMoc1EIwRibxPuzOFQt1GXvTav8WJ77mfjjiR_M_vBrPJRu0BaU_5ePrmV5KUvKhEj_AM_pcOc</recordid><startdate>19860801</startdate><enddate>19860801</enddate><creator>Tisdale, Patricia L</creator><creator>Collier, B. David</creator><creator>Kauffman, H. Myron</creator><creator>Adams, Mark B</creator><creator>Isitman, Ali T</creator><creator>Hellman, Robert S</creator><creator>Hoffmann, Raymond G</creator><creator>Rao, Shyam A</creator><creator>Joestgen, Thomas</creator><creator>Krohn, Linda</creator><general>Soc Nuclear Med</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19860801</creationdate><title>Early Diagnosis of Acute Postoperative Renal Transplant Rejection by Indium-111-Labeled Platelet Scintigraphy</title><author>Tisdale, Patricia L ; Collier, B. David ; Kauffman, H. Myron ; Adams, Mark B ; Isitman, Ali T ; Hellman, Robert S ; Hoffmann, Raymond G ; Rao, Shyam A ; Joestgen, Thomas ; Krohn, Linda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h238t-4ee25d8cb5687a36d39e1e1f8b15e6f6df1466906ca8290f9e944984ecad1a873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Blood Platelets</topic><topic>Female</topic><topic>Graft Rejection</topic><topic>Humans</topic><topic>Indium</topic><topic>Kidney - diagnostic imaging</topic><topic>Kidney Transplantation</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Period</topic><topic>Prospective Studies</topic><topic>Radioisotopes</topic><topic>Radionuclide Imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tisdale, Patricia L</creatorcontrib><creatorcontrib>Collier, B. David</creatorcontrib><creatorcontrib>Kauffman, H. Myron</creatorcontrib><creatorcontrib>Adams, Mark B</creatorcontrib><creatorcontrib>Isitman, Ali T</creatorcontrib><creatorcontrib>Hellman, Robert S</creatorcontrib><creatorcontrib>Hoffmann, Raymond G</creatorcontrib><creatorcontrib>Rao, Shyam A</creatorcontrib><creatorcontrib>Joestgen, Thomas</creatorcontrib><creatorcontrib>Krohn, Linda</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nuclear medicine (1978)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tisdale, Patricia L</au><au>Collier, B. David</au><au>Kauffman, H. Myron</au><au>Adams, Mark B</au><au>Isitman, Ali T</au><au>Hellman, Robert S</au><au>Hoffmann, Raymond G</au><au>Rao, Shyam A</au><au>Joestgen, Thomas</au><au>Krohn, Linda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early Diagnosis of Acute Postoperative Renal Transplant Rejection by Indium-111-Labeled Platelet Scintigraphy</atitle><jtitle>The Journal of nuclear medicine (1978)</jtitle><addtitle>J Nucl Med</addtitle><date>1986-08-01</date><risdate>1986</risdate><volume>27</volume><issue>8</issue><spage>1266</spage><epage>1272</epage><pages>1266-1272</pages><issn>0161-5505</issn><eissn>1535-5667</eissn><abstract>A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA and [131I]orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.</abstract><cop>United States</cop><pub>Soc Nuclear Med</pub><pmid>3525780</pmid><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 0161-5505 |
| ispartof | The Journal of nuclear medicine (1978), 1986-08, Vol.27 (8), p.1266-1272 |
| issn | 0161-5505 1535-5667 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Acute Disease Adolescent Adult Blood Platelets Female Graft Rejection Humans Indium Kidney - diagnostic imaging Kidney Transplantation Male Middle Aged Postoperative Period Prospective Studies Radioisotopes Radionuclide Imaging |
| title | Early Diagnosis of Acute Postoperative Renal Transplant Rejection by Indium-111-Labeled Platelet Scintigraphy |
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