Early Diagnosis of Acute Postoperative Renal Transplant Rejection by Indium-111-Labeled Platelet Scintigraphy

Early Diagnosis of Acute Postoperative Renal Transplant Rejection by Indium-111-Labeled Platelet Scintigraphy

A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA an...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Journal of nuclear medicine (1978) 1986-08, Vol.27 (8), p.1266-1272
Hauptverfasser: Tisdale, Patricia L, Collier, B. David, Kauffman, H. Myron, Adams, Mark B, Isitman, Ali T, Hellman, Robert S, Hoffmann, Raymond G, Rao, Shyam A, Joestgen, Thomas, Krohn, Linda
Format: Artikel
Sprache:eng
Schlagworte:
Acute Disease
Adolescent
Adult
Blood Platelets
Female
Graft Rejection
Humans
Indium
Kidney - diagnostic imaging
Kidney Transplantation
Male
Middle Aged
Postoperative Period
Prospective Studies
Radioisotopes
Radionuclide Imaging
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA and [131I]orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.
ISSN:0161-5505
1535-5667