Hepatic metastases of choriocarcinoma: A report of 15 patients
The presentation of illness, response to treatment, and complications of therapy of 15 patients with hepatic metastases of choriocarcinoma are analyzed. The majority of patients received multiagent chemotherapy concomitantly with whole-liver irradiation. Two patients are now in sustained remission....
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| Veröffentlicht in: | Gynecologic oncology 1986-09, Vol.25 (1), p.73-83 |
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| container_end_page | 83 |
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| container_issue | 1 |
| container_start_page | 73 |
| container_title | Gynecologic oncology |
| container_volume | 25 |
| creator | Barnard, David E. Woodward, Kent T. Yancy, Susan G. Weed, John C. Hammond, Charles B. |
| description | The presentation of illness, response to treatment, and complications of therapy of 15 patients with hepatic metastases of choriocarcinoma are analyzed. The majority of patients received multiagent chemotherapy concomitantly with whole-liver irradiation. Two patients are now in sustained remission. Hepatotoxicity of this combined treatment regimen directly contributed to only one death in the 13 nonsurviving patients. The diagnosis, management, and prognostic significance of choriocarcinoma metastatic to the liver are discussed. |
| doi_str_mv | 10.1016/0090-8258(86)90067-3 |
| format | Article |
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The majority of patients received multiagent chemotherapy concomitantly with whole-liver irradiation. Two patients are now in sustained remission. Hepatotoxicity of this combined treatment regimen directly contributed to only one death in the 13 nonsurviving patients. The diagnosis, management, and prognostic significance of choriocarcinoma metastatic to the liver are discussed.</description><identifier>ISSN: 0090-8258</identifier><identifier>EISSN: 1095-6859</identifier><identifier>DOI: 10.1016/0090-8258(86)90067-3</identifier><identifier>PMID: 3732921</identifier><identifier>CODEN: GYNOA3</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Choriocarcinoma - mortality ; Choriocarcinoma - pathology ; Choriocarcinoma - therapy ; Combined Modality Therapy ; Diseases of mother, fetus and pregnancy ; Female ; Gynecology. Andrology. Obstetrics ; Humans ; Liver Neoplasms - secondary ; Medical Records ; Medical sciences ; Middle Aged ; Pregnancy ; Pregnancy. Fetus. 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The majority of patients received multiagent chemotherapy concomitantly with whole-liver irradiation. Two patients are now in sustained remission. Hepatotoxicity of this combined treatment regimen directly contributed to only one death in the 13 nonsurviving patients. The diagnosis, management, and prognostic significance of choriocarcinoma metastatic to the liver are discussed.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Choriocarcinoma - mortality</subject><subject>Choriocarcinoma - pathology</subject><subject>Choriocarcinoma - therapy</subject><subject>Combined Modality Therapy</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Liver Neoplasms - secondary</subject><subject>Medical Records</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pregnancy</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Prognosis</subject><subject>Uterine Neoplasms - mortality</subject><subject>Uterine Neoplasms - pathology</subject><subject>Uterine Neoplasms - therapy</subject><issn>0090-8258</issn><issn>1095-6859</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMotVb_gcIeRPSwmmw2Xx4KRdQKBS96DtnZWYx0m5psBf-9u7b0KAzk8D7vMHkIOWf0llEm7yg1NNeF0Nda3hhKpcr5ARkzakQutTCHZLxHjslJSp-UUk5ZMSIjrnhhCjYm0zmuXecha7FzqR9MWWgy-AjRB3AR_Cq07j6bZRHXIXZDyEQ2dHDVpVNy1LhlwrPdOyHvT49vD_N88fr88jBb5MC17PIGhNFVZYqqUQ4c8hp1gaXihmMpVUGBCxDgoCp4WYtSsBIrqhFljUorxifkart3HcPXBlNnW58Al0u3wrBJVkkjZP-nHiy3IMSQUsTGrqNvXfyxjNpBmx2c2MGJ1dL-abO8r13s9m-qFut9aeepzy93uUvglk10K_BpjyktS0VFj023GPYuvj1Gm6D3BFj7iNDZOvj_7_gFXIiH-g</recordid><startdate>19860901</startdate><enddate>19860901</enddate><creator>Barnard, David E.</creator><creator>Woodward, Kent T.</creator><creator>Yancy, Susan G.</creator><creator>Weed, John C.</creator><creator>Hammond, Charles B.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19860901</creationdate><title>Hepatic metastases of choriocarcinoma: A report of 15 patients</title><author>Barnard, David E. ; Woodward, Kent T. ; Yancy, Susan G. ; Weed, John C. ; Hammond, Charles B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-fc598bb92bf7acae3de82e47393e46720c35c5cacb234d54514eb08ee6de78713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Choriocarcinoma - mortality</topic><topic>Choriocarcinoma - pathology</topic><topic>Choriocarcinoma - therapy</topic><topic>Combined Modality Therapy</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Liver Neoplasms - secondary</topic><topic>Medical Records</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pregnancy</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Prognosis</topic><topic>Uterine Neoplasms - mortality</topic><topic>Uterine Neoplasms - pathology</topic><topic>Uterine Neoplasms - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barnard, David E.</creatorcontrib><creatorcontrib>Woodward, Kent T.</creatorcontrib><creatorcontrib>Yancy, Susan G.</creatorcontrib><creatorcontrib>Weed, John C.</creatorcontrib><creatorcontrib>Hammond, Charles B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gynecologic oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barnard, David E.</au><au>Woodward, Kent T.</au><au>Yancy, Susan G.</au><au>Weed, John C.</au><au>Hammond, Charles B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hepatic metastases of choriocarcinoma: A report of 15 patients</atitle><jtitle>Gynecologic oncology</jtitle><addtitle>Gynecol Oncol</addtitle><date>1986-09-01</date><risdate>1986</risdate><volume>25</volume><issue>1</issue><spage>73</spage><epage>83</epage><pages>73-83</pages><issn>0090-8258</issn><eissn>1095-6859</eissn><coden>GYNOA3</coden><abstract>The presentation of illness, response to treatment, and complications of therapy of 15 patients with hepatic metastases of choriocarcinoma are analyzed. The majority of patients received multiagent chemotherapy concomitantly with whole-liver irradiation. Two patients are now in sustained remission. Hepatotoxicity of this combined treatment regimen directly contributed to only one death in the 13 nonsurviving patients. The diagnosis, management, and prognostic significance of choriocarcinoma metastatic to the liver are discussed.</abstract><cop>San Diego, CA</cop><pub>Elsevier Inc</pub><pmid>3732921</pmid><doi>10.1016/0090-8258(86)90067-3</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Gynecologic oncology, 1986-09, Vol.25 (1), p.73-83 |
| issn | 0090-8258 1095-6859 |
| language | eng |
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| source | MEDLINE; ScienceDirect Freedom Collection (Elsevier) |
| subjects | Adult Biological and medical sciences Choriocarcinoma - mortality Choriocarcinoma - pathology Choriocarcinoma - therapy Combined Modality Therapy Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics Humans Liver Neoplasms - secondary Medical Records Medical sciences Middle Aged Pregnancy Pregnancy. Fetus. Placenta Prognosis Uterine Neoplasms - mortality Uterine Neoplasms - pathology Uterine Neoplasms - therapy |
| title | Hepatic metastases of choriocarcinoma: A report of 15 patients |
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