Hepatic metastases of choriocarcinoma: A report of 15 patients

The presentation of illness, response to treatment, and complications of therapy of 15 patients with hepatic metastases of choriocarcinoma are analyzed. The majority of patients received multiagent chemotherapy concomitantly with whole-liver irradiation. Two patients are now in sustained remission....

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Veröffentlicht in:	Gynecologic oncology 1986-09, Vol.25 (1), p.73-83
Hauptverfasser:	Barnard, David E., Woodward, Kent T., Yancy, Susan G., Weed, John C., Hammond, Charles B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Choriocarcinoma - mortality Choriocarcinoma - pathology Choriocarcinoma - therapy Combined Modality Therapy Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics Humans Liver Neoplasms - secondary Medical Records Medical sciences Middle Aged Pregnancy Pregnancy. Fetus. Placenta Prognosis Uterine Neoplasms - mortality Uterine Neoplasms - pathology Uterine Neoplasms - therapy
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Zusammenfassung:	The presentation of illness, response to treatment, and complications of therapy of 15 patients with hepatic metastases of choriocarcinoma are analyzed. The majority of patients received multiagent chemotherapy concomitantly with whole-liver irradiation. Two patients are now in sustained remission. Hepatotoxicity of this combined treatment regimen directly contributed to only one death in the 13 nonsurviving patients. The diagnosis, management, and prognostic significance of choriocarcinoma metastatic to the liver are discussed.
ISSN:	0090-8258 1095-6859
DOI:	10.1016/0090-8258(86)90067-3