Detection of brain autoantibodies in the serum of patients with Alzheimer's disease but not down's syndrome

The immunofluorescent staining of antibodies specifically binding to rat brain tissue sections was investigated in 95 human sera including 30 cases of Alzheimer's disease. A high incidence of specific antibrain antibody was found among Alzheimer's patients (57% positive) compared to other...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Immunology letters 1986-06, Vol.12 (5), p.277-280
Hauptverfasser:	Singh, Vijendra K., Hugh Fudenberg, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Factors Aged Alzheimer Disease - immunology Alzheimer's disease Autoantibodies - isolation & purification Brain - immunology brain autoantibodies Down Syndrome - immunology Humans Middle Aged Multiple Sclerosis - immunology Parkinson Disease - immunology Schizophrenia - immunology specific binding
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The immunofluorescent staining of antibodies specifically binding to rat brain tissue sections was investigated in 95 human sera including 30 cases of Alzheimer's disease. A high incidence of specific antibrain antibody was found among Alzheimer's patients (57% positive) compared to other neurological disease controls (only 8% positive) or normal young and aged healthy controls (none positive).
ISSN:	0165-2478 1879-0542
DOI:	10.1016/0165-2478(86)90030-1