Thrombogenicity of an Elastomer-Coated Aortofemoral Dacron Prosthetic Graft in Humans

To determine the potential benefit of Dacron prostheses impregnated with silicon polymer, an elastomer-coated prosthetic graft (Intervascular [I]) was implanted in 30 patients with aortic occlusive arterial disease or infrarenal abdominal aortic aneurysm. These patients were compared with two other groups who underwent vascular reconstruction with either a knitted double-velour prosthesis (Meadox [M]) or a knitted prosthesis (Bard-USCI [U]). The different prostheses were randomly allocated just prior to their insertion. Average blood loss was 1063.33 ± 1065.69 ml for the I group, 888.33 ± 575.85 ml for the M group, and 908.33 ± 471.80 ml for the U group (NS). The duration of the operation was 160 ± 56 minutes for the I group, 142 ± 37 minutes for the M group, and 153 ± 65 minutes for the U group (NS). The average follow-up was 12 months. As calculated by the actuarial method, primary patency at 36 months was 71.5% for the I group, 100% for the M group, and 98.2% for the U group ( p