Cutaneous T-cell lymphoma diagnosed by fine-needle aspiration: A case report with clinical, cytological, and immunophenotypic features

A case study of cutaneous T‐cell lymphoma in a 40‐yr‐old Indian male is presented. Prominent clinical features consisted of large skin tumours, lymphidenopathy, and a rapidly progressive course of development. Aspiration smears from tumours, lymph nodes, and bone marrow showed pleomorphic Sezary cells and lymphoid blasts. The neoplastic cells stained positively with anti‐HLA DR, CD1, and CD2 antibodies and showed lack of T‐cell subset antigens CD4 and CD8. Numerous proliferating cells were identified with 56% of bone marrow cells and 57% of cells in the dermis staining positively with Ki‐67 and PC10 antibodies, respectively. This case is reported in view of its uncommon features. Diagn Cytopathol 1994;11:174–177. © 1994 Wiley‐Liss, Inc.