Use of monoclonal antibody for the detection of Lassa virus antibody and antigen in patients with Lassa fever

Experiments were carried out to detect LV antigen in human serum samples. The monoclonal antibodies were isolated from cell culture fluids and labelled with peroxidase; they were then employed in the authors enzyme immunoassay which measures adherence of immune complexes to rheumatoid factor (RF) bo...

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Veröffentlicht in:	Medical microbiology and immunology 1986-01, Vol.175 (2-3), p.181-182
Hauptverfasser:	Schmitz, H, Wolf, H R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Anti-Idiotypic - immunology Antibodies, Monoclonal - immunology Antibodies, Viral - analysis Antigen-Antibody Complex - analysis Antigens, Viral - analysis Cercopithecus aethiops Humans Immunoenzyme Techniques Lassa Fever - diagnosis Lassa Fever - immunology Mice Mice, Inbred BALB C Rheumatoid Factor
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Zusammenfassung:	Experiments were carried out to detect LV antigen in human serum samples. The monoclonal antibodies were isolated from cell culture fluids and labelled with peroxidase; they were then employed in the authors enzyme immunoassay which measures adherence of immune complexes to rheumatoid factor (RF) bound to a solid phase.
ISSN:	0300-8584 1432-1831
DOI:	10.1007/BF02122445