Opiate antagonists for the treatment of schizophrenia

SUMMARY Numerous studies suggest that opiate antagonists may have antipsychotic properties. A review of the literature describing the use of naloxone to treat schizophrenic patients has shown mixed results. The three studies on naltrexone have found no benefit in controlling auditory hallucinations....

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Veröffentlicht in:	Journal of clinical pharmacy and therapeutics 1994-10, Vol.19 (5), p.279-283
Hauptverfasser:	Welch, E. B., Thompson, D. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Hallucinations - drug therapy Humans Medical sciences Naloxone - therapeutic use Naltrexone - therapeutic use Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Schizophrenia - drug therapy
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Zusammenfassung:	SUMMARY Numerous studies suggest that opiate antagonists may have antipsychotic properties. A review of the literature describing the use of naloxone to treat schizophrenic patients has shown mixed results. The three studies on naltrexone have found no benefit in controlling auditory hallucinations. We present a synopsis of these studies.
ISSN:	0269-4727 1365-2710
DOI:	10.1111/j.1365-2710.1994.tb00814.x