A Diagnostic Quartet in Leptomeningeal Infiltration of the Optic Nerve Sheath

A rare case of optic leptomeningeal carcinomatosis secondary to a rectal adenocarcinoma is recorded. The presentation of rectal disease with blindness is unique. A diagnostic quartet of symptoms and signs of leptomeningeal infiltration of the optic nerve sheath is proposed and its value emphasized b...

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Veröffentlicht in:	Journal of neuro-ophthalmology 1994-09, Vol.14 (3), p.175-182
Hauptverfasser:	McFadzean, Robert, Brosnahan, Donal, Doyle, David, Going, James, Hadley, Donald, Lee, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - secondary Adult Biological and medical sciences Blindness - diagnosis Cranial Nerve Neoplasms - secondary Gastroenterology. Liver. Pancreas. Abdomen Humans Male Medical sciences Meningeal Neoplasms - diagnostic imaging Meningeal Neoplasms - secondary Myelin Sheath - pathology Optic Nerve Diseases - pathology Pupil Disorders - diagnosis Radiography Rectal Neoplasms - pathology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Subarachnoid Space Tumors
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Zusammenfassung:	A rare case of optic leptomeningeal carcinomatosis secondary to a rectal adenocarcinoma is recorded. The presentation of rectal disease with blindness is unique. A diagnostic quartet of symptoms and signs of leptomeningeal infiltration of the optic nerve sheath is proposed and its value emphasized by the inability of further investigation to confirm the clinical diagnosis. The investigation and treatment of leptomeningeal carcinomatosis is reviewed.
ISSN:	1070-8022 1536-5166
DOI:	10.1097/00041327-199409000-00010