IgA Nephropathy Associated with Portal Hypertension in Liver Cirrhosis due to Non-Alcoholic and Non-A, Non-B, Non-C Hepatitis
A 69-year-old female was admitted to our hospital because of leg edema, proteinuria (2.1 g/day), and gross hematuria. She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomeruloneph...
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Veröffentlicht in: | Internal Medicine 1994, Vol.33(8), pp.488-491 |
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creator | NAKAMURA, Mono OHISHI, Akira WATANABE, Reiko KANEKO, Kohtaro AOSAKI, Noboru IIGAYA, Tomohiko MONMA, Tetsuo SUGIURA, Hitoshi MIYOSHI, Yukari HAMAGUCHI, Kinichi |
description | A 69-year-old female was admitted to our hospital because of leg edema, proteinuria (2.1 g/day), and gross hematuria. She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomerulonephritis with IgA deposits. Propranolol was administered orally to reduce portal hypertension, resulting in a progressive decrease in urinary microalbumin excretion. This case suggests that portal hypertension is involved in the pathogenesis of IgA nephropathy in liver cirrhosis. (Internal Medicine 33: 488-491, 1994) |
doi_str_mv | 10.2169/internalmedicine.33.488 |
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She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomerulonephritis with IgA deposits. Propranolol was administered orally to reduce portal hypertension, resulting in a progressive decrease in urinary microalbumin excretion. This case suggests that portal hypertension is involved in the pathogenesis of IgA nephropathy in liver cirrhosis. 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(Internal Medicine 33: 488-491, 1994)</description><subject>Aged</subject><subject>Female</subject><subject>Glomerulonephritis, IGA - etiology</subject><subject>Glomerulonephritis, IGA - pathology</subject><subject>Hepatitis - complications</subject><subject>Hepatitis - pathology</subject><subject>Humans</subject><subject>Hypertension, Portal - drug therapy</subject><subject>Hypertension, Portal - etiology</subject><subject>Hypertension, Portal - pathology</subject><subject>Kidney Glomerulus - ultrastructure</subject><subject>Liver Cirrhosis - etiology</subject><subject>Liver Cirrhosis - pathology</subject><subject>liver disease</subject><subject>mesangial proliferative glomerulonephritis</subject><subject>Microscopy, Electron</subject><subject>Propranolol - therapeutic use</subject><subject>β-blocker</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplUE2P0zAUtBBoKQs_AeETJ1L81dg-lordrlQte4Cz5TgvG69SO9guqAf-O-mm6gEub6Q382b0BqEPlCwZrfVnHwqkYIc9tN75AEvOl0KpF2hBudCVZHz1Ei2Ipqpi03iN3uT8RAhXUrMrdCUV4ZrKBfpz97jG9zD2KY629Ee8zjk6bwu0-LcvPX6IqdgBb48jpAIh-xiwD3jnf0HCG59SH7PPuD0ALhHfx1CtBxf7OHiHbWjnzadn-DLDBm9hyvLF57foVWeHDO_OeI1-3Hz9vtlWu2-3d5v1rnKCPn9Qt41tuWYrSiQTkq-EYpxyK4STtVMCatq5hjSNYFKuVGOt62TbiY7yGhS_Rh9n3zHFnwfIxex9djAMNkA8ZCNrTYSWJ6GchS7FnBN0Zkx-b9PRUGJOxZt_izecm6n46fL9OeLQTNzl7tz0xD_M_FMu9hEuvE3FuwH-86Vas5O3mscUcZG63iYDgf8FyFqhdQ</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>NAKAMURA, Mono</creator><creator>OHISHI, Akira</creator><creator>WATANABE, Reiko</creator><creator>KANEKO, Kohtaro</creator><creator>AOSAKI, Noboru</creator><creator>IIGAYA, Tomohiko</creator><creator>MONMA, Tetsuo</creator><creator>SUGIURA, Hitoshi</creator><creator>MIYOSHI, Yukari</creator><creator>HAMAGUCHI, Kinichi</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>IgA Nephropathy Associated with Portal Hypertension in Liver Cirrhosis due to Non-Alcoholic and Non-A, Non-B, Non-C Hepatitis</title><author>NAKAMURA, Mono ; OHISHI, Akira ; WATANABE, Reiko ; KANEKO, Kohtaro ; AOSAKI, Noboru ; IIGAYA, Tomohiko ; MONMA, Tetsuo ; SUGIURA, Hitoshi ; MIYOSHI, Yukari ; HAMAGUCHI, Kinichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4118-296dbad392510724735482313a44c76c84e61fcb0bb427758baacf7df4f136e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Aged</topic><topic>Female</topic><topic>Glomerulonephritis, IGA - etiology</topic><topic>Glomerulonephritis, IGA - pathology</topic><topic>Hepatitis - complications</topic><topic>Hepatitis - pathology</topic><topic>Humans</topic><topic>Hypertension, Portal - drug therapy</topic><topic>Hypertension, Portal - etiology</topic><topic>Hypertension, Portal - pathology</topic><topic>Kidney Glomerulus - ultrastructure</topic><topic>Liver Cirrhosis - etiology</topic><topic>Liver Cirrhosis - pathology</topic><topic>liver disease</topic><topic>mesangial proliferative glomerulonephritis</topic><topic>Microscopy, Electron</topic><topic>Propranolol - therapeutic use</topic><topic>β-blocker</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>NAKAMURA, Mono</creatorcontrib><creatorcontrib>OHISHI, Akira</creatorcontrib><creatorcontrib>WATANABE, Reiko</creatorcontrib><creatorcontrib>KANEKO, Kohtaro</creatorcontrib><creatorcontrib>AOSAKI, Noboru</creatorcontrib><creatorcontrib>IIGAYA, Tomohiko</creatorcontrib><creatorcontrib>MONMA, Tetsuo</creatorcontrib><creatorcontrib>SUGIURA, Hitoshi</creatorcontrib><creatorcontrib>MIYOSHI, Yukari</creatorcontrib><creatorcontrib>HAMAGUCHI, Kinichi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NAKAMURA, Mono</au><au>OHISHI, Akira</au><au>WATANABE, Reiko</au><au>KANEKO, Kohtaro</au><au>AOSAKI, Noboru</au><au>IIGAYA, Tomohiko</au><au>MONMA, Tetsuo</au><au>SUGIURA, Hitoshi</au><au>MIYOSHI, Yukari</au><au>HAMAGUCHI, Kinichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>IgA Nephropathy Associated with Portal Hypertension in Liver Cirrhosis due to Non-Alcoholic and Non-A, Non-B, Non-C Hepatitis</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>1994</date><risdate>1994</risdate><volume>33</volume><issue>8</issue><spage>488</spage><epage>491</epage><pages>488-491</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A 69-year-old female was admitted to our hospital because of leg edema, proteinuria (2.1 g/day), and gross hematuria. She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomerulonephritis with IgA deposits. Propranolol was administered orally to reduce portal hypertension, resulting in a progressive decrease in urinary microalbumin excretion. This case suggests that portal hypertension is involved in the pathogenesis of IgA nephropathy in liver cirrhosis. (Internal Medicine 33: 488-491, 1994)</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>7803917</pmid><doi>10.2169/internalmedicine.33.488</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Female Glomerulonephritis, IGA - etiology Glomerulonephritis, IGA - pathology Hepatitis - complications Hepatitis - pathology Humans Hypertension, Portal - drug therapy Hypertension, Portal - etiology Hypertension, Portal - pathology Kidney Glomerulus - ultrastructure Liver Cirrhosis - etiology Liver Cirrhosis - pathology liver disease mesangial proliferative glomerulonephritis Microscopy, Electron Propranolol - therapeutic use β-blocker |
title | IgA Nephropathy Associated with Portal Hypertension in Liver Cirrhosis due to Non-Alcoholic and Non-A, Non-B, Non-C Hepatitis |
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