IgA Nephropathy Associated with Portal Hypertension in Liver Cirrhosis due to Non-Alcoholic and Non-A, Non-B, Non-C Hepatitis

A 69-year-old female was admitted to our hospital because of leg edema, proteinuria (2.1 g/day), and gross hematuria. She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomeruloneph...

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Veröffentlicht in:Internal Medicine 1994, Vol.33(8), pp.488-491
Hauptverfasser: NAKAMURA, Mono, OHISHI, Akira, WATANABE, Reiko, KANEKO, Kohtaro, AOSAKI, Noboru, IIGAYA, Tomohiko, MONMA, Tetsuo, SUGIURA, Hitoshi, MIYOSHI, Yukari, HAMAGUCHI, Kinichi
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container_end_page 491
container_issue 8
container_start_page 488
container_title Internal Medicine
container_volume 33
creator NAKAMURA, Mono
OHISHI, Akira
WATANABE, Reiko
KANEKO, Kohtaro
AOSAKI, Noboru
IIGAYA, Tomohiko
MONMA, Tetsuo
SUGIURA, Hitoshi
MIYOSHI, Yukari
HAMAGUCHI, Kinichi
description A 69-year-old female was admitted to our hospital because of leg edema, proteinuria (2.1 g/day), and gross hematuria. She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomerulonephritis with IgA deposits. Propranolol was administered orally to reduce portal hypertension, resulting in a progressive decrease in urinary microalbumin excretion. This case suggests that portal hypertension is involved in the pathogenesis of IgA nephropathy in liver cirrhosis. (Internal Medicine 33: 488-491, 1994)
doi_str_mv 10.2169/internalmedicine.33.488
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subjects Aged
Female
Glomerulonephritis, IGA - etiology
Glomerulonephritis, IGA - pathology
Hepatitis - complications
Hepatitis - pathology
Humans
Hypertension, Portal - drug therapy
Hypertension, Portal - etiology
Hypertension, Portal - pathology
Kidney Glomerulus - ultrastructure
Liver Cirrhosis - etiology
Liver Cirrhosis - pathology
liver disease
mesangial proliferative glomerulonephritis
Microscopy, Electron
Propranolol - therapeutic use
β-blocker
title IgA Nephropathy Associated with Portal Hypertension in Liver Cirrhosis due to Non-Alcoholic and Non-A, Non-B, Non-C Hepatitis
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