Infective endocarditis due to penicillin-tolerant Streptococcus bovis

Two Streptococcus bovis isolates obtained from patients with endocarditis were found to be tolerant to penicillin and other cell wall active agents. By time-kill analysis, penicillin and streptomycin acted synergistically against these strains. The existence of tolerant S . bovis strains should be c...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 1986-07, Vol.5 (2), p.171-176
Hauptverfasser:	Fung, Joan C., Gadbaw, Joseph J., Donta, Sam T., Tilton, Richard C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Bacterial diseases Bacterial endocarditis, myocarditis and pericarditis. Bacterial diseases of the aorta, limb vessels and lymphatic vessels Biological and medical sciences Drug Resistance, Microbial Endocarditis, Bacterial - drug therapy Endocarditis, Bacterial - microbiology Human bacterial diseases Humans Infectious diseases Male Medical sciences Streptococcal Infections - drug therapy Streptococcus - drug effects
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Zusammenfassung:	Two Streptococcus bovis isolates obtained from patients with endocarditis were found to be tolerant to penicillin and other cell wall active agents. By time-kill analysis, penicillin and streptomycin acted synergistically against these strains. The existence of tolerant S . bovis strains should be considered when initially choosing antibiotics for the treatment of serious S . bovis infections.
ISSN:	0732-8893 1879-0070
DOI:	10.1016/0732-8893(86)90119-7