The stereochemical course of group II intron self-splicing

The stereochemical specificities and reaction courses for both self-splicing steps of a group II intron have been determined by phosphorothioate substitution at the 5' and 3' splice site phosphodiester bonds. Both steps of the splicing reaction proceeded with a phosphorothioate in the Sp c...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1994-12, Vol.266 (5191), p.1685-1688
Hauptverfasser:	Padgett, R.A. (University of Texas Southwestern Medical Ceter at Dallas, Dallas, TX.), Podar, M, Boulanger, S.C, Perlman, P.S
Format:	Artikel
Sprache:	eng
Schlagworte:	ARN MENSAJERO ARN MESSAGER Base Sequence Biochemistry Biological and medical sciences CHIMIE Evolution Exons Fundamental and applied biological sciences. Psychology Gels Introns Molecular and cellular biology Molecular genetics Molecular Sequence Data Nucleic Acid Conformation Oligonucleotides Oligoribonucleotides - chemistry Oxygen Oxygen - chemistry Phosphorus Phosphorus - chemistry Product labeling QUIMICA Ribonucleic acid RNA RNA - chemistry RNA - genetics RNA Splicing SACCHAROMYCES CEREVISIAE Splicing Sulfur Sulfur - chemistry Thionucleotides - chemistry Transcription. Transcription factor. Splicing. Rna processing
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