Pharmacologic stress dual-isotope myocardial perfusion single-photon emission computed tomography

Separate-acquisition rest thallium-201/exercise technetium-99m sestamibi (sestamibi) dual-isotope single-photon emission computed tomography (SPECT) has been shown to be effective for assessment of myocardial perfusion and viability. The present study was designed to validate the dual-isotope approa...

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Veröffentlicht in:	The American heart journal 1994-12, Vol.128 (6), p.1067-1076
Hauptverfasser:	Matzer, Lisa, Kiat, Hosen, Wang, Fan Ping, Van Train, Kenneth, Germano, Guido, Friedman, John, Berman, Daniel S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Aged Biological and medical sciences Coronary Angiography Coronary Disease - diagnostic imaging Dipyridamole Feasibility Studies Female Heart Ventricles - diagnostic imaging Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Myocardial Infarction - diagnostic imaging Radionuclide investigations Respiratory system Sensitivity and Specificity Stress, Physiological - chemically induced Technetium Tc 99m Sestamibi Thallium Radioisotopes Tomography, Emission-Computed, Single-Photon - methods
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Zusammenfassung:	Separate-acquisition rest thallium-201/exercise technetium-99m sestamibi (sestamibi) dual-isotope single-photon emission computed tomography (SPECT) has been shown to be effective for assessment of myocardial perfusion and viability. The present study was designed to validate the dual-isotope approach when used in conjunction with pharmacologic stress. All patients had rest 201TI SPECT followed immediately by adenosine ( n = 82) or dipyridamole ( n = 50) infusion and sestamibi injection. Sestamibi SPECT was performed 1 hour later. The entire study lasted
ISSN:	0002-8703 1097-6744
DOI:	10.1016/0002-8703(94)90735-8