Identification of multiple, novel, protein kinase C-related gene products

Identification of multiple, novel, protein kinase C-related gene products

A PCR approach has been employed to screen two cDNA libraries for PKC(-related) sequences. In each case multiple cDNAs were identified, including known PKC isotypes, a previously unknown PKC-η related sequence and three members of what appears to be a protein kinase C related kinase (PRK 1–3) family...

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Veröffentlicht in:FEBS letters 1994-12, Vol.356 (1), p.5-8
Hauptverfasser: Palmer, R.H., Ridden, J., Parker, P.J.
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acid Sequence
brain
cDNA
Cell Line
DNA, Complementary
Humans
man
Molecular Sequence Data
monocytes
nucleotide sequence
PCR
Polymerase Chain Reaction
prediction
PRK1 gene
Protein kinase
Protein kinase C
Protein Kinase C - genetics
protein kinase C-related kinase
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Zusammenfassung:A PCR approach has been employed to screen two cDNA libraries for PKC(-related) sequences. In each case multiple cDNAs were identified, including known PKC isotypes, a previously unknown PKC-η related sequence and three members of what appears to be a protein kinase C related kinase (PRK 1–3) family. The origin and relationships of these predicted proteins is discussed.
ISSN:0014-5793
1873-3468
DOI:10.1016/0014-5793(94)01202-4