Divalent Cations Elevate Cytosolic Calcium of Chick Osteocytes

Divalent Cations Elevate Cytosolic Calcium of Chick Osteocytes

Though it is proposed that osteocytes have several functions in bone metabolism, only limited definite information including results of calcium regulation has been forthcoming. We demonstrate here for the first time that the concentration of divalent cations, such as calcium, nickel and cadmium, dir...

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Veröffentlicht in:Biochemical and biophysical research communications 1994-10, Vol.204 (2), p.519-524
Hauptverfasser: Kamioka, H., Sumitani, K., Tagami, K., Miki, Y., Terai, K., Hakeda, Y., Kumegawa, M., Kawata, T.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cadmium - pharmacology
Calcium - metabolism
Calcium - pharmacology
Cells, Cultured
Chick Embryo
Cytosol - metabolism
Nickel - pharmacology
Osteocytes - drug effects
Osteocytes - metabolism
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Beschreibung
Zusammenfassung:Though it is proposed that osteocytes have several functions in bone metabolism, only limited definite information including results of calcium regulation has been forthcoming. We demonstrate here for the first time that the concentration of divalent cations, such as calcium, nickel and cadmium, directly regulates the cytosolic calcium concentration in osteocytes.
ISSN:0006-291X
1090-2104
DOI:10.1006/bbrc.1994.2490