Induction of mutants resistant to antibiotics in Brevibacterium flavum

The optimum conditions for the induction of mutants resistant to antibiotics in Brevibacterium flavum ATCC 14067 were determined. UV irradiation at the energy fluence of 6.5 kJ/m2 and N-methyl-N'-nitro-N-nitrosoguanidine (1 mg/mL) at pH 6.0 were used for the induction of mutants. Mutant strains...

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Veröffentlicht in:	Folia microbiologica 1986-01, Vol.31 (2), p.94-97
Hauptverfasser:	KONICEK, J, KONICKOVA-RADOCHOVA, M, RYTIR, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacteriology Biological and medical sciences Brevibacterium - drug effects Brevibacterium - genetics Brevibacterium - radiation effects Brevibacterium flavum Drug Resistance, Microbial Erythromycin - pharmacology Fundamental and applied biological sciences. Psychology Genetics Hydrogen-Ion Concentration Methylnitronitrosoguanidine - pharmacology Microbiology Mutation Neomycin - pharmacology Oleandomycin - pharmacology Rifampin - pharmacology Streptomycin - pharmacology Ultraviolet Rays Vancomycin - pharmacology
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Zusammenfassung:	The optimum conditions for the induction of mutants resistant to antibiotics in Brevibacterium flavum ATCC 14067 were determined. UV irradiation at the energy fluence of 6.5 kJ/m2 and N-methyl-N'-nitro-N-nitrosoguanidine (1 mg/mL) at pH 6.0 were used for the induction of mutants. Mutant strains resistant to rifampicin, oleandomycin, streptomycin and erythromycin were prepared.
ISSN:	0015-5632 1874-9356
DOI:	10.1007/BF02926825